Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17974169 | 0.83 | HTT (0.32) | HTR2A | |
| SCHEMBL17974167 | 0.73 | TP53 (0.37) | — | |
| SCHEMBL17959934 | 0.71 | SLC6A4 (0.40) | SLC6A4 | |
| SCHEMBL4714505 | 0.70 | AKR1B1 (0.44) | HTR2ASLC6A4 | |
| SCHEMBL22368460 | 0.70 | POLB (0.35) | — | |
| SCHEMBL22368461 | 0.68 | AKR1B1 (0.35) | — | |
| SCHEMBL4667749 | 0.66 | HTR2A (0.53) | HTR2A | |
| SCHEMBL8343455 | 0.66 | BACE1 (0.36) | HTR2A | |
| SCHEMBL10754629 | 0.65 | HTR2A (0.34) | HTR2A | |
| SCHEMBL5677891 | 0.65 | HTR2A (0.42) | HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3253755-B1 | NOVEL CYCLOPROPABENZOFURANYL PYRIDOPYRAZINEDIONES | PFIZER (US) | 2020-08-26 | — | — | EP | disclosed |