Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 3/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | BRS3 | P32247 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PREP | P48147 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19990906 | 1.00 | CD274 (0.41) | CD274CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL22368499 | 1.00 | CD274 (0.41) | CD274CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL21981530 | 0.79 | KDM4E (0.45) | MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL19990744 | 0.79 | KDM4E (0.45) | MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL19990745 | 0.79 | KDM4E (0.45) | MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL22368471 | 0.79 | KDM4E (0.45) | MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL27495098 | 0.73 | HPGD (0.54) | BRD4MAPTKMT2AALDH1A1 | |
| SCHEMBL20012750 | 0.70 | ALDH1A1 (0.44) | MEN1KMT2AALDH1A1 | |
| SCHEMBL22368493 | 0.70 | ALDH1A1 (0.44) | MEN1KMT2AALDH1A1 | |
| SCHEMBL21088072 | 0.70 | ALDH1A1 (0.44) | MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3698796-A1 | PHARMACEUTICAL COMBINATION OF A TRICYCLIC BETA-LACTAMASE INHIBITOR WITH SPECIFIC BETA-LACTAM ANTIBIOTICS | Novartis AG (CH) | 2020-08-26 | — | — | EP | disclosed |