Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | GALR2 | O43603 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 5/20 | 0.33 |
| ▸ | CDC25B | P30305 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | PKM | P14618 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1338313 | 0.89 | HCAR3 (0.43) | HCAR3EGFRHTTLMNAGALR2 | |
| SCHEMBL1337856 | 0.86 | HCAR3 (0.45) | HCAR3EGFRHTTLMNAGALR2 | |
| SCHEMBL30789457 | 0.86 | HCAR3 (0.45) | HCAR3EGFRHTTLMNAGALR2 | |
| SCHEMBL30698940 | 0.75 | POLB (0.42) | HCAR3EGFRHTTLMNAGALR2 | |
| SCHEMBL1585679 | 0.75 | POLB (0.42) | HCAR3EGFRHTTLMNAGALR2 | |
| SCHEMBL21989619 | 0.73 | HCAR3 (0.47) | HCAR3LMNAPOLBSMN1; SMN2MAPT | |
| SCHEMBL30674815 | 0.73 | HCAR3 (0.47) | HCAR3LMNAPOLBSMN1; SMN2MAPT | |
| SCHEMBL19497649 | 0.73 | HCAR3 (0.45) | HCAR3EGFRHTTLMNAGALR2 | |
| SCHEMBL18322039 | 0.71 | HCAR3 (0.43) | HCAR3HTTLMNAGALR2POLB | |
| SCHEMBL16428099 | 0.71 | HCAR3 (0.50) | HCAR3HTTLMNAPOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2361252-A1 | 3H-IMIDAZO [4, 5-C]PYRIDINE-6-CARBOXAMIDES AS ANTI -INFLAMMATORY AGENTS | Boehringer Ingelheim International GmbH (DE) | 2011-08-31 | — | — | EP | disclosed |
| WO-2010034798-A1 | 3H-IMIDAZO [4, 5-C] PYRIDINE-6-CARBOXAMIDES AS ANTI -INFLAMMATORY AGENTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-04-01 | — | — | WO | disclosed |