SCHEMBL2237276

SCHEMBL2237276

O=Cc1cc(Br)c(C=O)cc1Br

nearest known ligand 0.58

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PRKDC P78527 1/20 0.58
LMNA P02545 3/20 0.52
ERN1 O75460 6/20 0.48
TDP1 Q9NUW8 2/20 0.40
MEN1 O00255 1/20 0.40
THRB P10828 1/20 0.40
BLM P54132 1/20 0.40
KMT2A Q03164 1/20 0.40
TRIM24 O15164 1/20 0.37
TRIM33 Q9UPN9 1/20 0.37
ALDH1A1 P00352 2/20 0.37
POLB P06746 1/20 0.37
MAPT P10636 1/20 0.37
HPGD P15428 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
PTPN1 P18031 1/20 0.36
CYP2A6 P11509 3/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18382141 0.94 PRKDC (0.54) PRKDCLMNAERN1TDP1MEN1
SCHEMBL1162124 0.90 PRKDC (0.56) PRKDCLMNAERN1TDP1MEN1
SCHEMBL31649818 0.87 ERN1 (0.48) PRKDCLMNAERN1TDP1MEN1
SCHEMBL6782431 0.84 ERN1 (0.48) PRKDCLMNAERN1TRIM24TRIM33
SCHEMBL709748 0.83 PRKDC (0.50) PRKDCLMNAERN1TDP1MEN1
SCHEMBL10018128 0.81 PRKDC (0.54) PRKDCLMNAERN1TDP1ALDH1A1
SCHEMBL21356041 0.81 PRKDC (0.48) PRKDCLMNAERN1TDP1MEN1
SCHEMBL29952291 0.81 PRKDC (0.48) PRKDCLMNAERN1TDP1MEN1
SCHEMBL2336761 0.81 ERN1 (0.50) PRKDCLMNAERN1TRIM24TRIM33
SCHEMBL29818613 0.79 PRKDC (0.47) PRKDCLMNAERN1MEN1BLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 210 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122038010-A Lubricating grease composition with excellent heat resistance stability, and preparation method and application thereof 思潞博(河南)新材料有限公司 2026-05-15 CN claimed
CN-119857380-A Gas separation membrane based on metal organic cage and preparation method and application thereof 天津大学 2025-04-22 CN claimed
CN-118663082-B Multilayer composite bionic structure oxygenation membrane and preparation method and application thereof 天津大学 2025-03-07 CN claimed
CN-117567408-B Colorimetric-fluorescent probe for detecting tryptamine, test pen and method 中国科学院新疆理化技术研究所 2025-02-18 CN claimed
CN-119241789-A Br-COFs material and preparation method thereof, and preparation method of interfacial film of covalent organic framework material of lithium metal battery 华南理工大学 2025-01-03 CN claimed
CN-119219875-A Vinyl porous organic polymer and preparation method thereof 南开大学 2024-12-31 CN claimed
CN-118663082-A Multilayer composite bionic structure oxygenation membrane and preparation method and application thereof 天津大学 2024-09-20 CN claimed
CN-118634653-A Covalent organic framework modified high ion selective permeable membrane and preparation method and application thereof 上海欧格尼氢能科技有限公司 2024-09-13 CN claimed
CN-118359779-A Sp derived from carbonyl monomer2Carbon conjugated polymer and preparation method and application thereof 中国科学院宁波材料技术与工程研究所 2024-07-19 CN claimed
CN-118255643-A Condensed ring type organic diradical compound and preparation method and application thereof 湖南大学 2024-06-28 CN claimed
CN-114605318-A Perchlorate visual fluorescent probe molecule and preparation method thereof 中国科学院新疆理化技术研究所 2022-06-10 CN claimed
CN-114307671-A Preparation method of grafting modified covalent organic framework composite membrane pore channel and filter membrane thereof 天津大学 2022-04-12 CN claimed
CN-114259879-A Covalent organic framework composite membrane and in-situ polymerization preparation method thereof 天津大学 2022-04-01 CN claimed
CN-114146572-A Preparation method of amide chain segment embedded covalent organic framework composite membrane and filter membrane thereof 天津大学 2022-03-08 CN claimed
CN-113773245-A Water-soluble double-targeting near-infrared fluorescent probe and preparation method thereof 西安交通大学口腔医院 2021-12-10 CN claimed
CN-110684203-B Two-dimensional bromine-containing covalent organic framework compound and preparation method thereof 南京大学 2021-08-17 CN claimed
CN-112808006-A High-rejection-rate covalent organic framework membrane, and raw material composition and preparation method thereof 天津大学 2021-05-18 CN claimed
CN-109553757-B Naphthalene diimide acceptor polymer with two-dimensional structure and preparation method and application thereof 福州大学 2021-03-02 CN claimed
CN-110684203-A Two-dimensional bromine-containing covalent organic framework compound and preparation method thereof 南京大学 2020-01-14 CN claimed
CN-108912012-A A kind of power causes ratio off-color material and preparation method thereof 浙江工业大学 2018-11-30 CN claimed