Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKDC | P78527 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | ERN1 | O75460 | 5/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.35 |
| ▸ | CA3 | P07451 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2237276 | 0.81 | PRKDC (0.58) | PRKDCLMNAERN1POLBL3MBTL1 | |
| SCHEMBL15713801 | 0.80 | ERN1 (0.40) | PRKDCLMNAERN1CA1CA2 | |
| SCHEMBL1162124 | 0.78 | PRKDC (0.56) | PRKDCLMNAERN1POLBL3MBTL1 | |
| SCHEMBL19453388 | 0.78 | PRKDC (0.72) | PRKDCLMNAERN1POLBL3MBTL1 | |
| SCHEMBL29954443 | 0.76 | ERN1 (0.47) | PRKDCERN1CA1CA2CA9 | |
| SCHEMBL14695048 | 0.76 | PTK2 (0.47) | LMNAERN1PTK2ALDH1A1MEN1 | |
| SCHEMBL18382141 | 0.76 | PRKDC (0.54) | PRKDCLMNAERN1POLBL3MBTL1 | |
| SCHEMBL8024070 | 0.75 | TDP1 (0.40) | LMNAERN1PTK2ALDH1A1HPGD | |
| SCHEMBL15873472 | 0.75 | ERN1 (0.41) | PRKDCLMNAERN1CA1CA2 | |
| SCHEMBL29951151 | 0.73 | TDP1 (0.42) | PRKDCLMNAERN1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |