Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C5AR1 | P21730 | 2/20 | 0.46 |
| ▸ | TFPI | P10646 | 1/20 | 0.45 |
| ▸ | GLP1R | P43220 | 6/20 | 0.44 |
| ▸ | SCTR | P47872 | 1/20 | 0.44 |
| ▸ | APLNR | P35414 | 1/20 | 0.44 |
| ▸ | IL23R | Q5VWK5 | 7/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22374849 | 0.91 | C5AR1 (0.47) | C5AR1TFPIGLP1RSCTRAPLNR | |
| SCHEMBL22374914 | 0.91 | IL23R (0.48) | GLP1RSCTRAPLNRIL23R | |
| SCHEMBL22375059 | 0.89 | TFPI (0.47) | C5AR1TFPIGLP1RSCTRAPLNR | |
| SCHEMBL22374947 | 0.85 | C5AR1 (0.46) | C5AR1TFPIGLP1RSCTRAPLNR | |
| SCHEMBL22374963 | 0.85 | C5AR1 (0.49) | C5AR1TFPIGLP1RSCTRAPLNR | |
| SCHEMBL22375041 | 0.84 | IL23R (0.50) | C5AR1TFPIIL23R | |
| SCHEMBL22374588 | 0.84 | C5AR1 (0.46) | C5AR1TFPIAPLNRIL23R | |
| SCHEMBL29904562 | 0.84 | C5AR1 (0.55) | C5AR1GLP1RSCTRAPLNR | |
| SCHEMBL22374516 | 0.84 | IL23R (0.49) | C5AR1TFPIIL23R | |
| SCHEMBL29904555 | 0.84 | NPY4R (0.53) | C5AR1IL23R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200268897-A1 | Phosphatase Binding Compounds and Methods of Using Same | YALE UNIVERSITY | 2020-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200268897-A1 | Phosphatase Binding Compounds and Methods of Using Same | PPP5C, PPP4C, DUSP26 | C5AR1 4658/4885TFPI 2882/4885GLP1R 2633/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.