Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY1 | P47900 | 1/20 | 0.37 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.35 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.34 |
| ▸ | APLNR | P35414 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 5/20 | 0.34 |
| ▸ | CNR2 | P34972 | 5/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22375253 | 0.99 | P2RY1 (0.37) | P2RY1SLC22A12NFE2L2TLR8SLC13A5 | |
| SCHEMBL22624032 | 0.96 | P2RY1 (0.39) | P2RY1SLC22A12NFE2L2TLR8SLC13A5 | |
| SCHEMBL21970992 | 0.80 | SLC22A12 (0.42) | P2RY1SLC22A12NFE2L2SLC13A5APLNR | |
| SCHEMBL21191754 | 0.79 | TLR8 (0.36) | P2RY1TLR8CNR1CNR2TLR7 | |
| SCHEMBL21191599 | 0.78 | TLR8 (0.35) | P2RY1TLR8CNR1CNR2TLR7 | |
| SCHEMBL21191591 | 0.76 | TLR8 (0.36) | P2RY1TLR8CNR1CNR2TLR7 | |
| SCHEMBL25101222 | 0.75 | TSHR (0.44) | TLR8TLR7TSHRLMNACYP2D6 | |
| SCHEMBL23419175 | 0.74 | SSTR4 (0.39) | TLR8CNR1CNR2TLR7TSHR | |
| SCHEMBL25101234 | 0.74 | TLR8 (0.40) | TLR8TLR7TSHRLMNAMEN1 | |
| SCHEMBL20313081 | 0.74 | CNR2 (0.49) | CNR1CNR2TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10959432-B2 | Microbiocidal oxadiazole derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2021-03-30 | — | — | US | disclosed |
| US-20200267986-A1 | Microbiocidal Oxadiazole Derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2020-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10959432-B2 | Microbiocidal oxadiazole derivatives | PRF1, NOX1, ARG1 | P2RY1 1221/4885SLC22A12 3208/4885NFE2L2 1776/4885 |
| US-20200267986-A1 | Microbiocidal Oxadiazole Derivatives | PRF1, NOX1, ARG1 | P2RY1 1221/4885SLC22A12 3208/4885NFE2L2 1776/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.