SCHEMBL22379486

SCHEMBL22379486

CC1(C)OB(c2cccc(C(F)(F)F)c2C#N)OC1(C)C

nearest known ligand 0.34

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LPL P06858 3/20 0.34
LIPG Q9Y5X9 3/20 0.34
KDM4E B2RXH2 9/20 0.33
ALDH1A1 P00352 9/20 0.33
HPGD P15428 5/20 0.33
GAA P10253 5/20 0.33
GLA P06280 3/20 0.33
LIPE Q05469 2/20 0.33
L3MBTL1 Q9Y468 5/20 0.33
SLC22A12 Q96S37 1/20 0.33
AR P10275 1/20 0.33
TDP1 Q9NUW8 4/20 0.32
MAPK1 P28482 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
TP53 P04637 1/20 0.32
P2RX7 Q99572 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29593103 0.84 SLC22A12 (0.32) KDM4EALDH1A1HPGDSLC22A12MAPK1
SCHEMBL2722288 0.83 SLC22A12 (0.33) KDM4EALDH1A1HPGDGAAGLA
SCHEMBL1534864 0.81 JAK2 (0.39) LPLLIPGKDM4EALDH1A1HPGD
SCHEMBL648182 0.80 CYP1A2 (0.40) LPLLIPGKDM4EALDH1A1
SCHEMBL23855810 0.80 LPL (0.35) LPLLIPG
SCHEMBL29382961 0.79 LPL (0.43) LPLLIPGALDH1A1LIPEL3MBTL1
SCHEMBL9755 0.79 LPL (0.43) LPLLIPGALDH1A1LIPEL3MBTL1
SCHEMBL18605390 0.78 LPL (0.34) LPLLIPG
SCHEMBL15156866 0.78 JAK2 (0.39) LPLLIPGKDM4EALDH1A1GAA
SCHEMBL13601624 0.78 LPL (0.37) LPLLIPGLIPE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11751474-B2 Compound and organic light emitting display device WUHAN TIANMA MICROELECTRONICS CO., LTD. (CN) 2023-09-05 US disclosed
US-11649254-B2 Compound, a display panel and an electronic device Wuhan Tianma Microelectronics Co., Ltd. Shanghai Branch (CN) 2023-05-16 US disclosed
US-11649254-B2 Compound, a display panel and an electronic device Wuhan Tianma Microelectronics Co., Ltd. Shanghai Branch (CN) 2023-05-16 US disclosed
US-20200270278-A1 COMPOUND, A DISPLAY PANEL AND AN ELECTRONIC DEVICE WUHAN TIANMA MICRO-ELECTRONICS CO., LTD. (CN) 2020-08-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11649254-B2 Compound, a display panel and an electronic device TEAD2, OCIAD2, TEAD4 LPL 635/4885LIPG 1961/4885KDM4E 3038/4885
US-20200270278-A1 COMPOUND, A DISPLAY PANEL AND AN ELECTRONIC DEVICE TEAD2, OCIAD2, TEAD4 LPL 635/4885LIPG 1961/4885KDM4E 3038/4885
US-11751474-B2 Compound and organic light emitting display device L1CAM, C1S, CCNE2 LPL 733/4885LIPG 2038/4885KDM4E 3712/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.