Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | COXFA4 | O00483 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.44 |
| ▸ | ODC1 | P11926 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 9/20 | 0.41 |
| ▸ | EPAS1 | Q99814 | 8/20 | 0.41 |
| ▸ | EP300 | Q09472 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16694297 | 0.82 | COXFA4 (0.52) | COXFA4CYP3A4MAPTSMN1; SMN2TP53 | |
| SCHEMBL16867638 | 0.82 | COXFA4 (0.52) | COXFA4CYP3A4MAPTSMN1; SMN2TP53 | |
| SCHEMBL16865490 | 0.78 | COXFA4 (0.49) | COXFA4CYP3A4MAPTSMN1; SMN2TP53 | |
| SCHEMBL16865546 | 0.78 | COXFA4 (0.49) | COXFA4CYP3A4MAPTSMN1; SMN2TP53 | |
| SCHEMBL16694172 | 0.73 | COXFA4 (0.59) | COXFA4CYP3A4HSP90AA1CYP1A2TSHR | |
| SCHEMBL16694253 | 0.73 | COXFA4 (0.49) | COXFA4CYP3A4MAPTSMN1; SMN2TP53 | |
| SCHEMBL16694415 | 0.70 | HIF1A (0.66) | COXFA4HSP90AA1HIF1AEPAS1EP300 | |
| SCHEMBL16865497 | 0.69 | COXFA4 (0.53) | COXFA4HSP90AA1HIF1AEPAS1EP300 | |
| SCHEMBL16865496 | 0.69 | COXFA4 (0.48) | COXFA4CYP3A4MAPTSMN1; SMN2TP53 | |
| SCHEMBL11398330 | 0.69 | COXFA4 (0.62) | COXFA4CYP3A4MAPTSMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3702783-A1 | METHODS FOR DETERMINING CELLS SUCH AS CIRCULATING CANCER OR FETAL CELLS | Analiza, Inc. (US) | 2020-09-02 | — | — | EP | disclosed |