SCHEMBL2238398

SCHEMBL2238398

CNC(=O)C(OC)c1ccccc1COc1cc(C)ccc1Cl

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FABP4 P15090 1/20 0.47
FABP5 Q01469 1/20 0.47
HDAC8 Q9BY41 2/20 0.43
NPC1 O15118 3/20 0.41
ATM Q13315 2/20 0.41
ALDH1A1 P00352 3/20 0.41
LMNA P02545 2/20 0.41
LPAR1 Q92633 2/20 0.40
MAPT P10636 3/20 0.39
MAPK1 P28482 2/20 0.39
KDM4E B2RXH2 2/20 0.39
MEN1 O00255 1/20 0.39
USP2 O75604 1/20 0.39
POLB P06746 1/20 0.39
CYP2C9 P11712 1/20 0.39
HPGD P15428 1/20 0.39
ALOX12 P18054 1/20 0.39
CYP2C19 P33261 1/20 0.39
KMT2A Q03164 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29371189 0.89 SMN1; SMN2 (0.45) FABP4FABP5ALDH1A1LMNALPAR1
SCHEMBL29368766 0.89 SMN1; SMN2 (0.45) FABP4FABP5ALDH1A1LMNALPAR1
SCHEMBL29365871 0.89 SMN1; SMN2 (0.45) FABP4FABP5ALDH1A1LMNALPAR1
SCHEMBL182597 0.89 SMN1; SMN2 (0.45) FABP4FABP5ALDH1A1LMNALPAR1
SCHEMBL16858325 0.89 SMN1; SMN2 (0.45) FABP4FABP5ALDH1A1LMNALPAR1
SCHEMBL29354984 0.89 SMN1; SMN2 (0.45) FABP4FABP5ALDH1A1LMNALPAR1
SCHEMBL230669 0.89 SMN1; SMN2 (0.45) FABP4FABP5ALDH1A1LMNALPAR1
SCHEMBL14906285 0.87 LPAR1 (0.47) NPC1ATMALDH1A1LPAR1MAPT
SCHEMBL15402001 0.87 MRGPRX4 (0.43) FABP4FABP5NPC1ALDH1A1LMNA
Acetamide SCHEMBL28557945 0.85 MEN1 (0.42) FABP4FABP5NPC1ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2348830-B1 SEED TREATMENT AGENT AND METHOD FOR PROTECTING PLANT SUMITOMO CHEMICAL CO (JP) 2016-09-14 EP disclosed
US-8293681-B2 Seed treatment agent and method for protecting plant SUMITOMO CHEMICAL COMPANY, LTD. (JP) 2012-10-23 US disclosed
US-20110197318-A1 Seed Treatment Agent and Method for Protecting Plant SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-08-11 US disclosed
EP-2348830-A1 SEED TREATMENT AGENT AND METHOD FOR PROTECTING PLANT Sumitomo Chemical Company, Limited (JP) 2011-08-03 EP disclosed
WO-2010032873-A1 SEED TREATMENT AGENT AND METHOD FOR PROTECTING PLANT SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-03-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110197318-A1 Seed Treatment Agent and Method for Protecting Plant MGAT2, MGAT1, ALB FABP4 1696/4885FABP5 1083/4885HDAC8 3843/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.