Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.50 |
| ▸ | BCL2 | P10415 | 1/20 | 0.49 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.48 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.48 |
| ▸ | CTSS | P25774 | 2/20 | 0.48 |
| ▸ | CTSK | P43235 | 2/20 | 0.48 |
| ▸ | CTSL | P07711 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15091844 | 0.90 | TACR1 (0.48) | ITGB3ITGA2BBCL2ITGA4ITGB7 | |
| SCHEMBL15037243 | 0.90 | TACR1 (0.48) | ITGB3ITGA2BBCL2ITGA4ITGB7 | |
| SCHEMBL25320494 | 0.89 | HDAC8 (0.58) | HDAC8ITGB3ITGA2BITGA4ITGB7 | |
| SCHEMBL15037032 | 0.88 | ITGB3 (0.54) | ITGB3ITGA2BBCL2CTSSCTSK | |
| SCHEMBL15091950 | 0.88 | ITGB3 (0.54) | ITGB3ITGA2BBCL2CTSSCTSK | |
| SCHEMBL15019911 | 0.87 | ITGB3 (0.48) | ITGB3ITGA2BBCL2ITGA4ITGB7 | |
| SCHEMBL15019914 | 0.87 | ITGB3 (0.48) | ITGB3ITGA2BBCL2ITGA4ITGB7 | |
| SCHEMBL22384149 | 0.85 | EPHX1 (0.44) | ITGB3ITGA2BBCL2CTSSCTSK | |
| SCHEMBL14190632 | 0.84 | ITGB3 (0.52) | HDAC8ITGB3ITGA2BBCL2ITGA4 | |
| SCHEMBL17834702 | 0.83 | ITGB3 (0.42) | ITGB3ITGA2BBCL2CTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3230276-B1 | GLP-1 RECEPTOR MODULATORS | CELGENE INT II SARL (CH) | 2020-09-02 | — | — | EP | disclosed |