Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16318110 | 0.97 | ACHE (0.34) | ACHEKMT2AEPHX1TDP1 | |
| SCHEMBL23945122 | 0.94 | EPHX1 (0.37) | ACHEKMT2AEPHX1 | |
| SCHEMBL20156487 | 0.94 | EPHX1 (0.37) | ACHEKMT2AEPHX1 | |
| SCHEMBL23945125 | 0.94 | EPHX1 (0.37) | ACHEKMT2AEPHX1 | |
| SCHEMBL21971979 | 0.94 | CYP2C9 (0.32) | ACHEEPHX1CA1CA2CA4 | |
| SCHEMBL20368999 | 0.85 | — | — | |
| SCHEMBL9256078 | 0.83 | ACHE (0.43) | ACHEKMT2AEPHX1CA1CA2 | |
| SCHEMBL9791506 | 0.83 | ACHE (0.43) | ACHEKMT2AEPHX1CA1CA2 | |
| Cycloheptane SCHEMBL23885013 | 0.83 | ACHE (0.43) | ACHEKMT2AEPHX1CA1CA2 | |
| SCHEMBL5189 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3230276-B1 | GLP-1 RECEPTOR MODULATORS | CELGENE INT II SARL (CH) | 2020-09-02 | — | — | EP | disclosed |