Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | S1PR5 | Q9H228 | 10/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 6/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.41 |
| ▸ | RARB | P10826 | 3/20 | 0.40 |
| ▸ | ITGB1 | P05556 | 3/20 | 0.40 |
| ▸ | ITGA4 | P13612 | 3/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16294794 | 0.89 | HRH2 (0.46) | HRH2HRH1S1PR5S1PR1S1PR3 | |
| SCHEMBL16294793 | 0.89 | HRH2 (0.46) | HRH2HRH1S1PR5S1PR1S1PR3 | |
| SCHEMBL20426686 | 0.88 | S1PR5 (0.51) | HRH2HRH1S1PR5S1PR1S1PR3 | |
| SCHEMBL20900665 | 0.88 | S1PR5 (0.51) | HRH2HRH1S1PR5S1PR1S1PR3 | |
| SCHEMBL20427358 | 0.88 | S1PR5 (0.51) | HRH2HRH1S1PR5S1PR1S1PR3 | |
| SCHEMBL16295823 | 0.86 | ITGB3 (0.49) | HRH2HRH1ITGB1ITGA4ITGB3 | |
| SCHEMBL16295824 | 0.86 | ITGB3 (0.49) | HRH2HRH1ITGB1ITGA4ITGB3 | |
| SCHEMBL20427117 | 0.86 | S1PR5 (0.47) | HRH2HRH1S1PR5S1PR1S1PR3 | |
| SCHEMBL16342890 | 0.85 | HRH2 (0.38) | HRH2HRH1S1PR5S1PR1S1PR3 | |
| SCHEMBL16342891 | 0.85 | HRH2 (0.38) | HRH2HRH1S1PR5S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3230276-B1 | GLP-1 RECEPTOR MODULATORS | CELGENE INT II SARL (CH) | 2020-09-02 | — | — | EP | disclosed |