Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 3/20 | 0.50 |
| ▸ | ITGA4 | P13612 | 3/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 10/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 10/20 | 0.48 |
| ▸ | KLKB1 | P03952 | 5/20 | 0.45 |
| ▸ | MME | P08473 | 1/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
| ▸ | CPA1 | P15085 | 1/20 | 0.42 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.42 |
| ▸ | PLG | P00747 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16306073 | 1.00 | ITGB1 (0.50) | ITGB1ITGA4ITGB3ITGA2BKLKB1 | |
| SCHEMBL16305712 | 1.00 | ITGB1 (0.50) | ITGB1ITGA4ITGB3ITGA2BKLKB1 | |
| SCHEMBL16305934 | 1.00 | ITGB1 (0.50) | ITGB1ITGA4ITGB3ITGA2BKLKB1 | |
| SCHEMBL16305708 | 1.00 | ITGB1 (0.50) | ITGB1ITGA4ITGB3ITGA2BKLKB1 | |
| SCHEMBL16305548 | 0.95 | ITGB1 (0.46) | ITGB1ITGA4ITGB3ITGA2BKLKB1 | |
| SCHEMBL16305367 | 0.95 | ITGB1 (0.45) | ITGB1ITGA4ITGB3ITGA2BKLKB1 | |
| SCHEMBL16305368 | 0.95 | ITGB1 (0.45) | ITGB1ITGA4ITGB3ITGA2BKLKB1 | |
| SCHEMBL22449249 | 0.95 | ITGB3 (0.51) | ITGB1ITGA4ITGB3ITGA2B | |
| SCHEMBL15037035 | 0.95 | ITGB3 (0.51) | ITGB1ITGA4ITGB3ITGA2B | |
| SCHEMBL22449285 | 0.95 | ITGB3 (0.51) | ITGB1ITGA4ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3230276-B1 | GLP-1 RECEPTOR MODULATORS | CELGENE INT II SARL (CH) | 2020-09-02 | — | — | EP | disclosed |