Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.53 |
| ▸ | DRD4 | P21917 | 1/20 | 0.53 |
| ▸ | DRD3 | P35462 | 1/20 | 0.53 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.46 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6538654 | 1.00 | DRD2 (0.53) | DRD2DRD4DRD3NR5A1MEN1 | |
| SCHEMBL8396301 | 0.88 | DRD2 (0.44) | DRD2DRD4DRD3NR5A1MEN1 | |
| SCHEMBL11523502 | 0.83 | DRD2 (0.54) | DRD2MEN1KMT2ATSHRLMNA | |
| SCHEMBL22384186 | 0.82 | MEN1 (0.57) | DRD2DRD4DRD3NR5A1MEN1 | |
| SCHEMBL16566163 | 0.82 | HRH3 (0.64) | DRD2DRD4DRD3NR5A1MEN1 | |
| SCHEMBL9797733 | 0.79 | RARB (0.49) | DRD2DRD4DRD3NR5A1MEN1 | |
| SCHEMBL9798799 | 0.79 | RARB (0.49) | DRD2DRD4DRD3NR5A1MEN1 | |
| SCHEMBL9797668 | 0.79 | RARB (0.49) | DRD2DRD4DRD3NR5A1MEN1 | |
| SCHEMBL8395822 | 0.78 | TSHR (0.43) | DRD2MEN1KMT2ATSHRHRH3 | |
| SCHEMBL9798260 | 0.78 | S1PR5 (0.59) | MEN1KMT2ATP53TSHRPLA2G4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3230276-B1 | GLP-1 RECEPTOR MODULATORS | CELGENE INT II SARL (CH) | 2020-09-02 | — | — | EP | disclosed |