Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 10/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 10/20 | 0.40 |
| ▸ | ITGB1 | P05556 | 4/20 | 0.37 |
| ▸ | ITGA4 | P13612 | 4/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | ITGAV | P06756 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | RARB | P10826 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20426081 | 0.93 | ITGB3 (0.43) | ITGB3ITGA2BITGB1ITGA4CYP3A4 | |
| SCHEMBL20426113 | 0.92 | ITGB3 (0.45) | ITGB3ITGA2BITGB1ITGA4CYP3A4 | |
| SCHEMBL20900636 | 0.92 | ITGB3 (0.41) | ITGB3ITGA2BITGB1ITGA4CYP3A4 | |
| SCHEMBL22384279 | 0.91 | ITGB1 (0.44) | ITGB3ITGA2BITGB1ITGA4CYP3A4 | |
| SCHEMBL16305830 | 0.89 | ITGB3 (0.43) | ITGB3ITGA2BITGB1ITGA4ITGAV | |
| SCHEMBL22756173 | 0.88 | PPARG (0.42) | ITGB3ITGA2BITGB1ITGA4PPARG | |
| SCHEMBL20900623 | 0.86 | ITGB3 (0.37) | ITGB3ITGA2BITGB1ITGA4PPARG | |
| SCHEMBL19806837 | 0.86 | PPARG (0.36) | ITGB3ITGA2BITGB1ITGA4PPARG | |
| SCHEMBL20900618 | 0.85 | ITGB1 (0.38) | ITGB3ITGA2BITGB1ITGA4PPARG | |
| SCHEMBL20900638 | 0.85 | ITGB3 (0.36) | ITGB3ITGA2BITGB1ITGA4ITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3230276-B1 | GLP-1 RECEPTOR MODULATORS | CELGENE INT II SARL (CH) | 2020-09-02 | — | — | EP | disclosed |