SCHEMBL22384199

CCCCCCOc1cccc(-c2noc(-c3cnc(C4=CC=C(C[C@H](NC(=O)c5ccc(C(C)(C)C)cc5)C(=O)NCCC(=O)O)C(C)C4)nc3)n2)c1

nearest known ligand 0.41

Predicted protein targets (top 13)

	gene	UniProt	supporting neighbours	confidence
▸	S1PR1	P21453	2/20	0.38

▸	GCGR	P47871	8/20	0.37

▸	PLG	P00747	1/20	0.35

▸	FAAH	O00519	1/20	0.35

▸	ADCY6	O43306	1/20	0.33

▸	ADCY3	O60266	1/20	0.33

▸	ADCY9	O60503	1/20	0.33

▸	ADCY5	O95622	1/20	0.33

▸	ADCY8	P40145	1/20	0.33

▸	ADCY7	P51828	1/20	0.33

▸	ADCY2	Q08462	1/20	0.33

▸	ADCY1	Q08828	1/20	0.33

▸	ADCY4	Q8NFM4	1/20	0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL16305663	0.86	PLG (0.44)	S1PR1GCGRPLGADCY6ADCY3
SCHEMBL16305662	0.84	PLG (0.43)	S1PR1GCGRPLGADCY6ADCY3
SCHEMBL16305658	0.77	GCGR (0.45)	S1PR1GCGRADCY6ADCY3ADCY9
SCHEMBL16305856	0.74	GCGR (0.46)	GCGRADCY6ADCY3ADCY9ADCY5
SCHEMBL16305696	0.74	SRC (0.45)	GCGRPLGADCY6ADCY3ADCY9
SCHEMBL16306096	0.74	SRC (0.45)	GCGRPLGADCY6ADCY3ADCY9
SCHEMBL16306008	0.74	SRC (0.45)	GCGRPLGADCY6ADCY3ADCY9
SCHEMBL16305719	0.73	GCGR (0.48)	S1PR1GCGRADCY6ADCY3ADCY9
SCHEMBL16305671	0.73	GCGR (0.45)	GCGRADCY6ADCY3ADCY9ADCY5
SCHEMBL16306007	0.73	L3MBTL1 (0.45)	GCGRPLGADCY6ADCY3ADCY9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-3230276-B1	GLP-1 RECEPTOR MODULATORS	CELGENE INT II SARL (CH)	2020-09-02	—	—	EP	disclosed