Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.38 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | STAT6 | P42226 | 2/20 | 0.35 |
| ▸ | STAT5A | P42229 | 2/20 | 0.35 |
| ▸ | STAT5B | P51692 | 2/20 | 0.35 |
| ▸ | PRCP | P42785 | 1/20 | 0.34 |
| ▸ | XIAP | P98170 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19465512 | 0.89 | ACE (0.46) | ACEUSP30STAT6STAT5ASTAT5B | |
| SCHEMBL17459612 | 0.89 | ACE (0.46) | ACEUSP30STAT6STAT5ASTAT5B | |
| SCHEMBL17459609 | 0.89 | ACE (0.46) | ACEUSP30STAT6STAT5ASTAT5B | |
| SCHEMBL17459610 | 0.89 | ACE (0.46) | ACEUSP30STAT6STAT5ASTAT5B | |
| SCHEMBL17834393 | 0.84 | ACE (0.46) | ACEUSP30STAT6STAT5ASTAT5B | |
| SCHEMBL17968865 | 0.81 | ACE (0.46) | ACESTAT6STAT5ASTAT5BPRCP | |
| SCHEMBL17968867 | 0.81 | ACE (0.46) | ACESTAT6STAT5ASTAT5BPRCP | |
| SCHEMBL17459564 | 0.81 | ACE (0.46) | ACESTAT6STAT5ASTAT5BPRCP | |
| SCHEMBL19465507 | 0.81 | ACE (0.46) | ACESTAT6STAT5ASTAT5BPRCP | |
| SCHEMBL16343394 | 0.78 | ACE (0.46) | ACEPRCPF2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3230276-B1 | GLP-1 RECEPTOR MODULATORS | CELGENE INT II SARL (CH) | 2020-09-02 | — | — | EP | disclosed |