Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.47 |
| ▸ | PLG | P00747 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.43 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.42 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | RARB | P10826 | 3/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | CBX4 | O00257 | 2/20 | 0.39 |
| ▸ | CBX7 | O95931 | 2/20 | 0.39 |
| ▸ | CDYL2 | Q8N8U2 | 2/20 | 0.39 |
| ▸ | CBX8 | Q9HC52 | 2/20 | 0.39 |
| ▸ | GCGR | P47871 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16305675 | 0.92 | PPARG (0.47) | PPARGPLGPPARAKLKB1ITGB1 | |
| SCHEMBL19544766 | 0.91 | PPARG (0.47) | PPARGPLGPPARAKLKB1ITGB1 | |
| SCHEMBL16305983 | 0.91 | PPARG (0.47) | PPARGPLGPPARAKLKB1ITGB1 | |
| SCHEMBL16306129 | 0.91 | PPARG (0.47) | PPARGPLGPPARAKLKB1ITGB1 | |
| SCHEMBL16295654 | 0.91 | PPARG (0.50) | PPARGPLGPPARAKLKB1ITGB1 | |
| SCHEMBL16305364 | 0.91 | PPARG (0.50) | PPARGPLGPPARAKLKB1ITGB1 | |
| SCHEMBL16295701 | 0.91 | PPARG (0.50) | PPARGPLGPPARAKLKB1ITGB1 | |
| SCHEMBL22756212 | 0.91 | PLG (0.48) | PPARGPLGPPARAKLKB1ITGB1 | |
| SCHEMBL16306232 | 0.91 | PPARG (0.50) | PPARGPLGPPARAKLKB1ITGB1 | |
| SCHEMBL19544654 | 0.91 | PLG (0.48) | PPARGPLGPPARAKLKB1ITGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3230276-B1 | GLP-1 RECEPTOR MODULATORS | CELGENE INT II SARL (CH) | 2020-09-02 | — | — | EP | disclosed |