Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 3/20 | 0.39 |
| ▸ | KIFC1 | Q9BW19 | 2/20 | 0.38 |
| ▸ | ACE | P12821 | 8/20 | 0.38 |
| ▸ | MME | P08473 | 8/20 | 0.38 |
| ▸ | ACE2 | Q9BYF1 | 7/20 | 0.38 |
| ▸ | CPA1 | P15085 | 6/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.36 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15037409 | 1.00 | KLKB1 (0.39) | KLKB1KIFC1ACEMMEACE2 | |
| SCHEMBL15037230 | 0.93 | MCL1 (0.38) | KLKB1KIFC1ACEMMEACE2 | |
| SCHEMBL15037350 | 0.93 | MCL1 (0.38) | KLKB1KIFC1ACEMMEACE2 | |
| SCHEMBL22384128 | 0.93 | MCL1 (0.38) | KLKB1KIFC1ACEMMEACE2 | |
| SCHEMBL15037234 | 0.93 | KIFC1 (0.38) | KLKB1KIFC1ACEMMEACE2 | |
| SCHEMBL15037085 | 0.93 | KIFC1 (0.38) | KLKB1KIFC1ACEMMEACE2 | |
| SCHEMBL17834867 | 0.92 | KIFC1 (0.43) | KIFC1ACEMMEACE2CPA1 | |
| SCHEMBL17968745 | 0.92 | KIFC1 (0.43) | KIFC1ACEMMEACE2CPA1 | |
| SCHEMBL15037392 | 0.92 | KIFC1 (0.43) | KIFC1ACEMMEACE2CPA1 | |
| SCHEMBL15037133 | 0.92 | KIFC1 (0.43) | KIFC1ACEMMEACE2CPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2791112-B1 | CARBOXYLIC ACID DERIVATIVES COMPRISING FOUR CYCLES ACTING AS GLP-1 RECEPTOR MODULATORS FOR THERAPY OF DISEASES SUCH AS DIABETES | CELGENE INT II SÀRL (CH) | 2020-09-23 | — | — | EP | disclosed |
| EP-3230276-B1 | GLP-1 RECEPTOR MODULATORS | CELGENE INT II SARL (CH) | 2020-09-02 | — | — | EP | disclosed |