Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 3/20 | 0.37 |
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.34 |
| ▸ | WDR5 | P61964 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | NOS2 | P35228 | 2/20 | 0.33 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | PRKACA | P17612 | 1/20 | 0.33 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.33 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.33 |
| ▸ | PRKX | P51817 | 1/20 | 0.33 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.33 |
| ▸ | PRKG2 | Q13237 | 1/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
| ▸ | PRKG1 | Q13976 | 1/20 | 0.33 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.33 |
| ▸ | HIPK4 | Q8NE63 | 1/20 | 0.33 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17834762 | 0.91 | CDK2 (0.38) | CDK2PPARGNOS2CTSLEED | |
| SCHEMBL17834890 | 0.83 | MME (0.37) | EEDKLKB1 | |
| SCHEMBL16305891 | 0.83 | MME (0.37) | EEDKLKB1 | |
| SCHEMBL16305890 | 0.83 | MME (0.37) | PPARGEEDKLKB1 | |
| SCHEMBL16306239 | 0.83 | MME (0.42) | EEDKLKB1 | |
| SCHEMBL17834725 | 0.83 | NPC1 (0.39) | NOS2CTSLEED | |
| SCHEMBL16306249 | 0.82 | MME (0.41) | WDR5KMT2AKLKB1KLK1 | |
| SCHEMBL22756211 | 0.82 | WDR5 (0.37) | WDR5KMT2AROCK2PRKACARPS6KB1 | |
| SCHEMBL17834893 | 0.82 | MME (0.41) | WDR5KMT2AKLKB1KLK1 | |
| SCHEMBL17834539 | 0.81 | MME (0.36) | EEDKLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3230276-B1 | GLP-1 RECEPTOR MODULATORS | CELGENE INT II SARL (CH) | 2020-09-02 | — | — | EP | disclosed |