⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11731243 | 0.77 | SMYD3 (0.30) | — | |
| SCHEMBL19489922 | 0.74 | — | — | |
| SCHEMBL123243 | 0.58 | — | — | |
| SCHEMBL19437280 | 0.55 | — | — | |
| SCHEMBL12777839 | 0.55 | — | — | |
| SCHEMBL1083825 | 0.53 | — | — | |
| SCHEMBL3669699 | 0.52 | KMO (0.48) | — | |
| SCHEMBL1993095 | 0.52 | KMO (0.34) | — | |
| SCHEMBL13037671 | 0.52 | KDM4E (0.56) | — | |
| SCHEMBL1995715 | 0.52 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2529388-B1 | FRAGMENTATION REAGENTS FOR MASS SPECTROMETRY | MICROMASS LTD (GB) | 2019-10-23 | — | — | EP | claimed |
| US-9159542-B2 | Apparatus and method for inhibiting ionization source filament failure | THERMO FINNIGAN LLC (US) | 2015-10-13 | — | — | US | claimed |
| US-20130214147-A1 | Apparatus and Method for Inhibiting Ionization Source Filament Failure | THERMO FINNIGAN LLC | 2013-08-22 | — | — | US | claimed |
| US-20130122599-A1 | Fragmentation Reagents For Mass Spectrometry | MICROMASS UK LIMITED (GB) | 2013-05-16 | — | — | US | claimed |
| EP-2529388-A1 | FRAGMENTATION REAGENTS FOR MASS SPECTROMETRY | Micromass UK Limited (GB) | 2012-12-05 | — | — | EP | claimed |
| EP-4665718-A1 | SMALL MOLECULES AS MONOACYLGLYCEROL LIPASE (MAGL) INHIBITORS, COMPOSITIONS AND USE THEREOF | Apogee Pharmaceuticals, Inc. (CA) | 2025-12-24 | — | — | EP | disclosed |
| US-12454529-B2 | Piperazine cyclic ureas | Sironax Ltd. (KY) | 2025-10-28 | — | — | US | disclosed |
| US-12378231-B2 | Small molecules as monoacylglycerol lipase (MAGL) inhibitors, compositions and use thereof | APOGEE PHARMACEUTICALS, INC. (CA) | 2025-08-05 | — | — | US | disclosed |
| CN-115697991-B | Piperazine cyclic ureas | 维泰瑞隆有限公司 | 2024-11-22 | — | — | CN | disclosed |
| US-20240382465-A1 | AROMATIC ACETYLENE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF | ZHEJIANG HISUN PHARMACEUTICAL CO., LTD. (CN) | 2024-11-21 | — | — | US | disclosed |
| US-20240294514-A1 | SMALL MOLECULES AS MONOACYLGLYCEROL LIPASE (MAGL) INHIBITORS, COMPOSITIONS AND USE THEREOF | APOGEE PHARMACEUTICALS, INC. (CA) | 2024-09-05 | — | — | US | disclosed |
| WO-2024168426-A1 | SMALL MOLECULES AS MONOACYLGLYCEROL LIPASE (MAGL) INHIBITORS, COMPOSITIONS AND USE THEREOF | APOGEE PHARMACEUTICALS, INC. (CA) | 2024-08-22 | — | — | WO | disclosed |
| US-20170073360-A1 | BETA-LACTAMASE INHIBITORS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2017-03-16 | — | — | US | disclosed |
| US-20160185761-A1 | Compounds for Enhancing the Cognitive Function | UCB PHARMA, S.A. (BE) | 2016-06-30 | — | — | US | disclosed |
| US-9159542-B2 | Apparatus and method for inhibiting ionization source filament failure | THERMO FINNIGAN LLC (US) | 2015-10-13 | — | — | US | disclosed |
| WO-2015014785-A1 | COMPOUNDS FOR ENHANCING THE COGNITIVE FUNCTION | UCB PHARMA, S.A. (BE) | 2015-02-05 | — | — | WO | disclosed |
| US-20130214147-A1 | Apparatus and Method for Inhibiting Ionization Source Filament Failure | THERMO FINNIGAN LLC | 2013-08-22 | — | — | US | disclosed |
| US-20130122599-A1 | Fragmentation Reagents For Mass Spectrometry | MICROMASS UK LIMITED (GB) | 2013-05-16 | — | — | US | disclosed |
| EP-2529388-A1 | FRAGMENTATION REAGENTS FOR MASS SPECTROMETRY | Micromass UK Limited (GB) | 2012-12-05 | — | — | EP | disclosed |
| WO-2011092515-A1 | FRAGMENTATION REAGENTS FOR MASS SPECTROMETRY | MICROMASS UK LIMITED (GB) | 2011-08-04 | — | — | WO | disclosed |