Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 9/20 | 0.74 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MRGPRX1 | Q96LB2 | 4/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TSPO | P30536 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL871856 | 1.00 | TLR4 (0.74) | TLR4LMNAKMT2AMRGPRX1NPSR1 | |
| SCHEMBL2234657 | 1.00 | TLR4 (0.74) | TLR4LMNAKMT2AMRGPRX1NPSR1 | |
| SCHEMBL872792 | 0.90 | TLR4 (0.60) | TLR4LMNAMRGPRX1TSPOHRH1 | |
| SCHEMBL871685 | 0.85 | TLR4 (1.00) | TLR4LMNAKMT2AMRGPRX1NPSR1 | |
| SCHEMBL2235300 | 0.85 | TLR4 (0.52) | TLR4LMNAKMT2AMRGPRX1NPSR1 | |
| SCHEMBL14108316 | 0.85 | TLR4 (0.52) | TLR4LMNAKMT2AMRGPRX1NPSR1 | |
| SCHEMBL2236172 | 0.85 | TLR4 (0.52) | TLR4LMNAKMT2AMRGPRX1NPSR1 | |
| Resatorvid SCHEMBL13944462 | 0.84 | TLR4 (0.73) | TLR4LMNAKMT2AMRGPRX1NPSR1 | |
| Resatorvid SCHEMBL13944475 | 0.84 | TLR4 (0.73) | TLR4LMNAKMT2AMRGPRX1NPSR1 | |
| Resatorvid SCHEMBL13944467 | 0.84 | TLR4 (0.79) | TLR4LMNAKMT2AMRGPRX1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011093512-A1 | COMPOUNDS FOR SUPPRESSING A PERIPHERAL NERVE DISORDER INDUCED BY AN ANTI - CANCER AGENT | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-08-04 | — | — | WO | disclosed |