Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 6/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 4/20 | 0.42 |
| ▸ | USP2 | O75604 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21806091 | 0.83 | ALDH1A1 (0.52) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL25431445 | 0.78 | MAPT (0.40) | MAPTNR1H4MEN1KMT2AKDM4E | |
| SCHEMBL25431450 | 0.78 | MAPT (0.40) | MAPTNR1H4MEN1KMT2AKDM4E | |
| SCHEMBL29761153 | 0.76 | ALDH1A1 (0.60) | MAPTNR1H4MEN1KMT2AKDM4E | |
| SCHEMBL17445577 | 0.76 | ALDH1A1 (0.60) | MAPTNR1H4MEN1KMT2AKDM4E | |
| SCHEMBL26073497 | 0.76 | CYP19A1 (0.57) | MAPTNR1H4MEN1KMT2AKDM4E | |
| SCHEMBL23419323 | 0.75 | MAPT (0.44) | MAPTNR1H4MEN1KMT2AKDM4E | |
| SCHEMBL26082908 | 0.75 | CYP19A1 (0.60) | MAPTNR1H4MEN1KMT2AKDM4E | |
| SCHEMBL28625138 | 0.74 | GBA1 (0.52) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL26082647 | 0.74 | CYP19A1 (0.57) | MAPTNR1H4MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200277670-A1 | TERTIARY AMINE SUBSTITUTED COUMARIN COMPOUNDS AND USES AS FLUORESCENT LABELS | ILLUMINA CAMBRIDGE LIMITED (GB) | 2020-09-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200277670-A1 | TERTIARY AMINE SUBSTITUTED COUMARIN COMPOUNDS AND USES AS FLUORESCENT LABELS | FBL, NAT10, DNMT3A | MAPT 1401/4885NR1H4 1499/4885MEN1 3144/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.