Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.50 |
| ▸ | PPARA | Q07869 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.49 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.49 |
| ▸ | APP | P05067 | 4/20 | 0.48 |
| ▸ | AHR | P35869 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10069015 | 0.87 | APP (0.58) | ALDH1A1MEN1KMT2AAPPAHR | |
| SCHEMBL22386553 | 0.85 | MEN1 (0.63) | PPARGPPARAALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL15355647 | 0.84 | APP (0.52) | ALDH1A1LMNACYP3A4APPAHR | |
| SCHEMBL20024696 | 0.82 | AHR (0.56) | ALDH1A1MEN1KMT2AAPPAHR | |
| SCHEMBL19142219 | 0.80 | APP (0.55) | ALDH1A1LMNASMN1; SMN2MEN1USP2 | |
| SCHEMBL25567286 | 0.79 | MEN1 (0.63) | PPARGPPARAALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL17230493 | 0.79 | TDP1 (0.55) | APP | |
| SCHEMBL23266068 | 0.79 | MEN1 (0.67) | ALDH1A1LMNASMN1; SMN2MEN1USP2 | |
| SCHEMBL2332173 | 0.79 | MEN1 (0.55) | ALDH1A1LMNASMN1; SMN2MEN1USP2 | |
| SCHEMBL2325119 | 0.79 | MEN1 (0.55) | ALDH1A1LMNASMN1; SMN2MEN1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200277406-A1 | BINDING AGENT | ROCHE DIAGNOSTICS GMBH (DE) | 2020-09-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200277406-A1 | BINDING AGENT | SSB, APBA1, SHBG | PPARG 4175/4885PPARA 3055/4885ALDH1A1 2473/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.