Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 16/20 | 0.64 |
| ▸ | DRD2 | P14416 | 8/20 | 0.64 |
| ▸ | DRD3 | P35462 | 8/20 | 0.64 |
| ▸ | HTR2C | P28335 | 5/20 | 0.63 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20847630 | 0.84 | DRD4 (0.69) | DRD4DRD2DRD3HTR2CHTR1A | |
| SCHEMBL22388781 | 0.79 | MELK (0.58) | DRD4DRD2DRD3 | |
| SCHEMBL6014220 | 0.78 | DRD4 (1.00) | DRD4DRD2DRD3HTR2CHTR1A | |
| SCHEMBL18965735 | 0.77 | DRD4 (0.70) | DRD4DRD2DRD3 | |
| SCHEMBL9607548 | 0.77 | GAA (0.53) | DRD4DRD2DRD3 | |
| SCHEMBL22388784 | 0.76 | MAPT (0.46) | DRD4DRD2DRD3 | |
| SCHEMBL22388785 | 0.75 | ADRB1 (0.47) | — | |
| SCHEMBL22388848 | 0.74 | DRD4 (0.56) | DRD4DRD2DRD3 | |
| SCHEMBL18965827 | 0.74 | DRD4 (0.64) | DRD4DRD2DRD3HTR1A | |
| SCHEMBL14094665 | 0.73 | DRD4 (0.68) | DRD4DRD2DRD3HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200277268-A1 | PENTAFLUOROPHENYL SULFONAMIDE COMPOUNDS, COMPOSITIONS AND USES THEREOF | DALRIADA THERAPEUTICS INC. (CA) | 2020-09-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200277268-A1 | PENTAFLUOROPHENYL SULFONAMIDE COMPOUNDS, COMPOSITIONS AND USES THEREOF | MKI67, PKD1, ETV6 | DRD4 4824/4885DRD2 4857/4885DRD3 4874/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.