Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.45 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18265983 | 0.88 | ALDH1A1 (0.51) | ALDH1A1SLC15A1HCAR2KMT2AMAPK1 | |
| SCHEMBL9011978 | 0.86 | ALDH1A1 (0.50) | ALDH1A1SLC15A1HCAR2KMT2AMAPK1 | |
| SCHEMBL25925590 | 0.84 | ALDH1A1 (0.47) | ALDH1A1SLC15A1KMT2AMAPK1L3MBTL1 | |
| SCHEMBL10098419 | 0.84 | ALDH1A1 (0.47) | ALDH1A1SLC15A1KMT2AMAPK1L3MBTL1 | |
| SCHEMBL12311397 | 0.81 | ALDH1A1 (0.42) | ALDH1A1SLC15A1KMT2AMAPK1L3MBTL1 | |
| SCHEMBL28247081 | 0.79 | ALDH1A1 (0.46) | ALDH1A1SLC15A1KMT2AMAPK1L3MBTL1 | |
| SCHEMBL621696 | 0.79 | ALDH1A1 (0.56) | ALDH1A1HCAR2KMT2AMAPK1L3MBTL1 | |
| SCHEMBL28371759 | 0.79 | ALDH1A1 (0.56) | ALDH1A1HCAR2KMT2AMAPK1L3MBTL1 | |
| SCHEMBL116845 | 0.79 | ALDH1A1 (0.56) | ALDH1A1HCAR2KMT2AMAPK1L3MBTL1 | |
| SCHEMBL2736911 | 0.79 | ALDH1A1 (0.49) | ALDH1A1HCAR2KMT2AMAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230241241-A1 | CONJUGATES OF A CELL-BINDING MOLECULE WITH CAMPTOTHECIN ANALOGS | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2023-08-03 | — | — | US | disclosed |
| US-20200276261-A1 | A CONJUGATE OF A TUBULYSIN ANALOG WITH BRANCHED LINKERS | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2020-09-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200276261-A1 | A CONJUGATE OF A TUBULYSIN ANALOG WITH BRANCHED LINKERS | TEKT1, TEK, BTN3A1 | ALDH1A1 4604/4885SLC15A1 262/4885HCAR2 1556/4885 |
| US-20230241241-A1 | CONJUGATES OF A CELL-BINDING MOLECULE WITH CAMPTOTHECIN ANALOGS | CD4, DCLRE1A, TOP1 | ALDH1A1 3405/4885SLC15A1 874/4885HCAR2 3343/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.