SCHEMBL22389559

SCHEMBL22389559

Clc1ccccc1C1=Cc2cc3ccc(cc4nc(cc5[nH]c(c(-c6ccccc6Cl)c1n2)c(-c1ccccc1Cl)c5-c1ccccc1Cl)C=C4)[nH]3.[Zn]

nearest known ligand 0.32

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 1/20 0.32
▸ NPC1 O15118 1/20 0.32
▸ ALDH1A1 P00352 1/20 0.32
▸ RAB9A P51151 1/20 0.32
▸ GPR55 Q9Y2T6 1/20 0.32
▸ PTGES O14684 7/20 0.32
▸ STAT3 P40763 1/20 0.31
▸ STAT1 P42224 1/20 0.31
▸ CYP3A4 P08684 1/20 0.31
▸ CYP2C9 P11712 1/20 0.31
▸ CYP2C19 P33261 1/20 0.31
▸ MAPK13 O15264 1/20 0.30
▸ RAF1 P04049 1/20 0.30
▸ MAPK12 P53778 1/20 0.30
▸ MAPK11 Q15759 1/20 0.30
▸ MAPK14 Q16539 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22389542 0.99 KDM4E (0.33) KDM4ENPC1ALDH1A1RAB9AGPR55
SCHEMBL10919663 0.98 KDM4E (0.32) KDM4ENPC1ALDH1A1RAB9AGPR55
SCHEMBL9764668 0.98 KDM4E (0.32) KDM4ENPC1ALDH1A1RAB9AGPR55
SCHEMBL9764619 0.98 KDM4E (0.32) KDM4ENPC1ALDH1A1RAB9AGPR55
SCHEMBL11324162 0.87 NPBWR1 (0.30) —
SCHEMBL22389525 0.86 NPC1 (0.33) NPC1ALDH1A1RAB9ASTAT3STAT1
SCHEMBL22389523 0.85 STAT3 (0.31) PTGESSTAT3STAT1
SCHEMBL22389541 0.85 NPC1 (0.33) NPC1ALDH1A1RAB9ASTAT3STAT1
SCHEMBL270828 0.84 MGAM (0.33) KDM4ENPC1ALDH1A1RAB9ASTAT3
SCHEMBL38285 0.84 NPC1 (0.33) KDM4ENPC1ALDH1A1RAB9ASTAT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11491711-B2 Method of making 3D printed objects using two distinct light sources PHOTOCENTRIC LIMITED (GB) 2022-11-08 — — US claimed
US-20200282638-A1 METHOD OF MAKING 3D PRINTED OBJECTS USING TWO DISTINCT LIGHT SOURCES PHOTOCENTRIC LIMITED (GB) 2020-09-10 — — US claimed
US-11498268-B2 Method of making 3D printed objects by dispensing sequential layers of material PHOTOCENTRIC LIMITED (GB) 2022-11-15 — — US disclosed
US-11491711-B2 Method of making 3D printed objects using two distinct light sources PHOTOCENTRIC LIMITED (GB) 2022-11-08 — — US disclosed
US-20200282638-A1 METHOD OF MAKING 3D PRINTED OBJECTS USING TWO DISTINCT LIGHT SOURCES PHOTOCENTRIC LIMITED (GB) 2020-09-10 — — US disclosed
US-20200282637-A1 METHOD OF MAKING 3D PRINTED OBJECTS BY DISPENSING SEQUENTIAL LAYERS OF MATERIAL PHOTOCENTRIC LIMITED (GB) 2020-09-10 — — US disclosed
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