Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 5/20 | 0.74 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.66 |
| ▸ | EGFR | P00533 | 1/20 | 0.65 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | USP2 | O75604 | 1/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.63 |
| ▸ | UBE2M | P61081 | 1/20 | 0.62 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | HTR1E | P28566 | 1/20 | 0.61 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25389220 | 1.00 | RXFP1 (0.74) | RXFP1EPHX2ALDH1A1KDM4EEGFR | |
| SCHEMBL19638388 | 0.99 | RXFP1 (0.73) | RXFP1EPHX2ALDH1A1KDM4EEGFR | |
| SCHEMBL15530059 | 0.91 | RXFP1 (0.71) | RXFP1EPHX2ALDH1A1LMNAMAPT | |
| SCHEMBL15530000 | 0.90 | RXFP1 (0.69) | RXFP1EPHX2ALDH1A1KDM4EEGFR | |
| SCHEMBL4297476 | 0.87 | RXFP1 (0.66) | RXFP1ALDH1A1KDM4EEGFRERBB4 | |
| Hydrochloric Acid SCHEMBL31435248 | 0.86 | RXFP1 (0.65) | RXFP1ALDH1A1KDM4EEGFRERBB4 | |
| SCHEMBL15529956 | 0.86 | RXFP1 (1.00) | RXFP1 | |
| SCHEMBL15528534 | 0.86 | RXFP1 (1.00) | RXFP1 | |
| SCHEMBL19745428 | 0.85 | KDM4E (0.62) | RXFP1ALDH1A1KDM4EEGFRERBB4 | |
| SCHEMBL15530097 | 0.84 | RXFP1 (1.00) | RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110195979-A1 | COMPOUNDS FOR THE TREATMENT AND PREVENTION OF INFLUENZA | F. HOFFMANN-LA ROCHE AG (CH) | 2011-08-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110195979-A1 | COMPOUNDS FOR THE TREATMENT AND PREVENTION OF INFLUENZA | NAT1, NHERF1, ADORA1 | RXFP1 25/4885EPHX2 4462/4885ALDH1A1 507/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.