Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.59 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 7/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10770561 | 0.94 | TSHR (0.70) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL11511750 | 0.92 | TSHR (0.54) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL11510328 | 0.92 | TSHR (0.54) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL72364 | 0.92 | TSHR (0.62) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL11740476 | 0.90 | TSHR (0.65) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL2240698 | 0.90 | TSHR (0.53) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL22115828 | 0.89 | TSHR (0.68) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL3903523 | 0.87 | TSHR (0.70) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL17712528 | 0.86 | TSHR (0.55) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL15407301 | 0.86 | TSHR (0.73) | TSHRTHRBALDH1A1POLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150191607-A1 | Anti-fouling Paints and Coatings | REACTIVE SURFACES, LTD (US) | 2015-07-09 | — | — | US | disclosed |
| US-7994250-B2 | Vinyl-urethane copolymers with intermediary linkage segments having silicon-oxygen bonds and production methods thereof | KONISHI CO., LTD. (JP) | 2011-08-09 | — | — | US | disclosed |
| US-20100210745-A1 | Molecular Healing of Polymeric Materials, Coatings, Plastics, Elastomers, Composites, Laminates, Adhesives, and Sealants by Active Enzymes | REACTIVE SURFACES, LTD. (US) | 2010-08-19 | — | — | US | disclosed |
| EP-1837360-A1 | VINYL-URETHANE COPOLYMER AND METHOD FOR PRODUCING SAME | Konishi Co., Ltd. (JP) | 2007-09-26 | — | — | EP | disclosed |
| US-20070117902-A1 | Vinyl-urethane copolymers and production methods thereof | KONISHI CO., LTD. (JP) | 2007-05-24 | — | — | US | disclosed |
| EP-0604677-B1 | Method of making coated shaped articles | MITSUBISHI RAYON CO (JP) | 1999-08-11 | — | — | EP | disclosed |
| US-5470616-A | Coated shaped articles and method of making same | MITSUBISHI RAYON CO., LTD. (JP) | 1995-11-28 | — | — | US | disclosed |
| EP-0604677-A1 | Coated shaped articles and method of making same | MITSUBISHI RAYON CO., LTD. (JP) | 1994-07-06 | — | — | EP | disclosed |
| EP-0135923-B1 | PRODUCTION OF WATER-CURABLE, SILANE MODIFIED THERMOPLASTIC POLYMERS | UNION CARBIDE CORPORATION (US) | 1989-09-20 | — | — | EP | disclosed |
| EP-0212630-A2 | Compositions based on water-curable thermoplastic polymers and metal carboxylate silanol condensation catalysts | UNION CARBIDE CORPORATION (US) | 1987-03-04 | — | — | EP | disclosed |
| EP-0135923-A2 | Production of water-curable, silane modified thermoplastic polymers | UNION CARBIDE CORPORATION (US) | 1985-04-03 | — | — | EP | disclosed |
| US-4133938-A | ACRYLOYLOXYALKYLALKOXYSILANE-ACRYLATE REACTION PRODUCT, MASONRY | SWS SILICONES CORPORATION (US) | 1979-01-09 | — | — | US | disclosed |
| US-4029842-A | POLYMETHYL METHACRYLATE COATED AND OVERCOATED WITH TRIALKOXYSILANES | JAPAN ATOMIC ENERGY RESEARCH INSTITUTE (JA) | 1977-06-14 | — | — | US | disclosed |
| US-4026826-A | ALKOXYSILANES | JAPAN ATOMIC ENERGY RESEARCH INSTITUTE (JA) | 1977-05-31 | — | — | US | disclosed |