Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11511750 | 0.97 | TSHR (0.54) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL25812321 | 0.93 | TSHR (0.57) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL2239148 | 0.92 | TSHR (0.59) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL6928063 | 0.90 | TSHR (0.57) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL192216 | 0.88 | TSHR (0.58) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL28333610 | 0.87 | TSHR (0.67) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL27709408 | 0.87 | TSHR (0.67) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL27521354 | 0.87 | TSHR (0.67) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL10770561 | 0.86 | TSHR (0.70) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL7639156 | 0.86 | THRB (0.51) | TSHRTHRBALDH1A1POLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4133938-A | ACRYLOYLOXYALKYLALKOXYSILANE-ACRYLATE REACTION PRODUCT, MASONRY | SWS SILICONES CORPORATION (US) | 1979-01-09 | — | — | US | disclosed |