Sugi Predict

Sugi Predict / Compounds / SCHEMBL22391815

SCHEMBL22391815

SCHEMBL22391815

CC(C)(C)OC(=O)N1CC=C(c2ccnc(OCc3ccc(Cl)cc3F)n2)CC1

nearest known ligand 0.48

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ GRM1 Q13255 10/20 0.48
▸ GRM5 P41594 9/20 0.48
▸ CNR1 P21554 2/20 0.45
▸ TLR7 Q9NYK1 1/20 0.43
▸ GPR119 Q8TDV5 2/20 0.42
▸ WNT3A P56704 1/20 0.42
▸ CDK9 P50750 2/20 0.42
▸ MKNK1 Q9BUB5 1/20 0.42
▸ CCNT1 O60563 1/20 0.42
▸ PDE10A Q9Y233 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29359060 1.00 GRM1 (0.48) GRM1GRM5CNR1TLR7GPR119
SCHEMBL26913997 0.88 GRM1 (0.47) GRM1GRM5CNR1TLR7GPR119
SCHEMBL28690457 0.88 KDM5A (0.42) CNR1
SCHEMBL24498578 0.88 GRM1 (0.46) GRM1GRM5TLR7GPR119WNT3A
SCHEMBL29668627 0.87 GRM1 (0.49) GRM1GRM5CNR1GPR119MKNK1
SCHEMBL24321526 0.87 GRM1 (0.49) GRM1GRM5CNR1GPR119MKNK1
SCHEMBL22391651 0.85 GRM1 (0.44) GRM1GRM5CNR1TLR7GPR119
SCHEMBL31306920 0.83 GRM1 (0.47) GRM1GRM5CNR1TLR7GPR119
SCHEMBL30583877 0.83 GRM5 (0.47) GRM1GRM5CNR1TLR7GPR119
SCHEMBL30583911 0.82 GRM5 (0.48) GRM1GRM5CNR1TLR7GPR119

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260035362-A1 GLP-1R AGONISTS AND USES THEREOF QILU REGOR THERAPEUTICS INC (CN) 2026-02-05 — — US disclosed
US-12365670-B2 GLP-IR agonists and uses thereof QILU REGOR THERAPEUTICS INC. (CN) 2025-07-22 — — US disclosed
CN-113227068-B GLP-1R agonists and uses thereof 上海齐鲁锐格医药研发有限公司 2023-06-13 — — CN disclosed
US-20220024901-A1 GLP-1R AGONISTS AND USES THEREOF QILU REGOR THERAPEUTICS INC. (CN) 2022-01-27 — — US disclosed
US-20220024901-A1 GLP-1R AGONISTS AND USES THEREOF QILU REGOR THERAPEUTICS INC. (CN) 2022-01-27 — — US disclosed
US-10844049-B2 GLP-1R agonists and uses thereof QILU REGOR THERAPEUTICS INC. (CN) 2020-11-24 — — US disclosed
US-10844049-B2 GLP-1R agonists and uses thereof QILU REGOR THERAPEUTICS INC. (CN) 2020-11-24 — — US disclosed
US-20200283424-A1 GLP-1R AGONISTS AND USES THEREOF QILU REGOR THERAPEUTICS INC. (CN) 2020-09-10 — — US disclosed
US-20200283424-A1 GLP-1R AGONISTS AND USES THEREOF QILU REGOR THERAPEUTICS INC. (CN) 2020-09-10 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260035362-A1 GLP-1R AGONISTS AND USES THEREOF GLP1R, GPR119, IAPP GRM1 1879/4885GRM5 2939/4885CNR1 213/4885
US-10844049-B2 GLP-1R agonists and uses thereof GLP1R, GPR119, GIPR GRM1 1475/4885GRM5 925/4885CNR1 279/4885
US-12365670-B2 GLP-IR agonists and uses thereof GLP1R, GPR119, GIPR GRM1 1234/4885GRM5 840/4885CNR1 581/4885
US-20200283424-A1 GLP-1R AGONISTS AND USES THEREOF GLP1R, GPR119, GIPR GRM1 1475/4885GRM5 925/4885CNR1 279/4885
US-20220024901-A1 GLP-1R AGONISTS AND USES THEREOF GLP1R, GPR119, GIPR GRM1 1208/4885GRM5 960/4885CNR1 400/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.