Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.37 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NCF1 | P14598 | 3/20 | 0.31 |
| ▸ | XDH | P47989 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30480644 | 1.00 | IRAK4 (0.37) | IRAK4PDE3BPDE3APDE10AAR | |
| SCHEMBL17137076 | 0.92 | IRAK4 (0.41) | IRAK4NCOA3SRCXDHALDH1A1 | |
| SCHEMBL17137481 | 0.85 | SRC (0.43) | IRAK4ARSRC | |
| SCHEMBL22396538 | 0.84 | HPGD (0.37) | IRAK4PDE3BPDE3APDE10AKDM4E | |
| SCHEMBL30480647 | 0.84 | HPGD (0.37) | IRAK4PDE3BPDE3APDE10AKDM4E | |
| SCHEMBL17151233 | 0.84 | XDH (0.40) | IRAK4ARNCOA3XDH | |
| SCHEMBL17137611 | 0.81 | TDP1 (0.42) | IRAK4PDE3AARSRCKDM4E | |
| SCHEMBL22396610 | 0.79 | AAK1 (0.40) | IRAK4PDE3BPDE3APDE10AXDH | |
| SCHEMBL17137087 | 0.79 | IRAK4 (0.39) | IRAK4NCOA3SRCXDHLMNA | |
| SCHEMBL18553944 | 0.78 | IRAK4 (0.37) | IRAK4PDE10ANCOA3KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111542516-B | IRAK4 inhibitors and uses thereof | 新标立亚医疗有限公司 | 2023-07-18 | — | — | CN | disclosed |
| US-20200385370-A1 | APPARATUS FOR REMOVING BAD ODOR FROM TOILET | SYNBLIA THERAPEUTICS, INC. | 2020-12-10 | — | — | US | disclosed |
| US-20200385370-A1 | APPARATUS FOR REMOVING BAD ODOR FROM TOILET | SYNBLIA THERAPEUTICS, INC. | 2020-12-10 | — | — | US | disclosed |
| EP-3704104-A1 | IRAK4 INHIBITORS AND USES THEREOF | Synblia Therapeutics, Inc. (US) | 2020-09-09 | — | — | EP | disclosed |
| CN-111542516-A | IRAK4 inhibitors and uses thereof | 新标立亚医疗有限公司 | 2020-08-14 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200385370-A1 | APPARATUS FOR REMOVING BAD ODOR FROM TOILET | IRAK4, IRAK1, IRAK2 | IRAK4 1/4885PDE3B 1021/4885PDE3A 1264/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.