Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATF4 | P18848 | 19/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19569642 | 1.00 | ATF4 (0.50) | ATF4POLB | |
| SCHEMBL22396700 | 0.91 | ATF4 (0.53) | ATF4 | |
| SCHEMBL22396986 | 0.90 | ATF4 (0.47) | ATF4 | |
| SCHEMBL19569337 | 0.90 | ATF4 (0.47) | ATF4 | |
| SCHEMBL30026111 | 0.90 | ATF4 (0.47) | ATF4 | |
| SCHEMBL19569747 | 0.90 | ATF4 (0.59) | ATF4 | |
| SCHEMBL19569452 | 0.90 | ATF4 (0.59) | ATF4 | |
| SCHEMBL31525210 | 0.90 | ATF4 (0.59) | ATF4 | |
| SCHEMBL30961497 | 0.90 | ATF4 (0.59) | ATF4 | |
| SCHEMBL19569455 | 0.90 | ATF4 (0.59) | ATF4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3704094-A1 | MODULATORS OF THE INTEGRATED STRESS PATHWAY | Calico Life Sciences LLC (US) | 2020-09-09 | — | — | EP | disclosed |