Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.93 |
| ▸ | DAO | P14920 | 1/20 | 0.93 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.93 |
| ▸ | CES2 | O00748 | 3/20 | 0.74 |
| ▸ | CES1 | P23141 | 3/20 | 0.74 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.74 |
| ▸ | TP53 | P04637 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 2/20 | 0.55 |
| ▸ | CA1 | P00915 | 2/20 | 0.55 |
| ▸ | CA2 | P00918 | 2/20 | 0.55 |
| ▸ | CA3 | P07451 | 2/20 | 0.55 |
| ▸ | CA4 | P22748 | 2/20 | 0.55 |
| ▸ | CA6 | P23280 | 2/20 | 0.55 |
| ▸ | CA5A | P35218 | 2/20 | 0.55 |
| ▸ | CA7 | P43166 | 2/20 | 0.55 |
| ▸ | CA9 | Q16790 | 2/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.55 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL6562140 | 1.00 | TSHR (0.93) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL28625110 | 0.97 | TSHR (0.88) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL28610947 | 0.97 | TSHR (0.88) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL28614921 | 0.97 | TSHR (0.88) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL29101151 | 0.97 | TSHR (0.88) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL28170990 | 0.97 | TSHR (0.88) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL29229358 | 0.97 | TSHR (0.88) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL3966600 | 0.97 | TSHR (1.00) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL976149 | 0.97 | TSHR (1.00) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL407365 | 0.97 | TSHR (1.00) | TSHRDAONAPRTCES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117736083-A | Method for preparing 2, 4-dichloro-5-fluorobenzoic acid and 2, 6-dichloro-3-fluorobenzoic acid by taking 2, 4-dichloro-5-fluoroacetophenone crystallization mother liquor as raw material | 浙江工业大学 | 2024-03-22 | — | — | CN | claimed |
| CN-213645176-U | Water bath oscillation cleaning device for fluorine-containing benzene carboxylic acid equipment | 福建润华化工有限公司 | 2021-07-09 | — | — | CN | claimed |
| CN-111382528-B | Multi-stage fracturing natural gas horizontal well tracing method based on artificial intelligence | 西南石油大学 | 2020-08-28 | — | — | CN | claimed |
| CN-111382528-A | Multi-stage fracturing natural gas horizontal well tracing method based on artificial intelligence | 西南石油大学 | 2020-07-07 | — | — | CN | claimed |
| CN-109469481-B | Chemical combination tracer and its application method | 北京大德广源石油技术服务有限公司 | 2019-09-03 | — | — | CN | claimed |
| CN-109575922-A | A kind of OLED ITO etching solution and its preparation method and application | 苏州晶瑞化学股份有限公司 | 2019-04-05 | — | — | CN | claimed |
| CN-109469481-A | Chemical combination tracer and its application method | 北京大德广源石油技术服务有限公司 | 2019-03-15 | — | — | CN | claimed |
| CN-106220569-B | A kind of quaternary halogen amine antibacterial precursor, preparation and the application process immobilized for inactive surfaces | 大连理工大学 | 2018-07-13 | — | — | CN | claimed |
| CN-107406469-A | For extraction from aqueous streamsGet C1To C4Quaternary arylcarboxylate salt compositions of carboxylic acids | 伊士曼化工公司 | 2017-11-28 | — | — | CN | claimed |
| CN-106220569-A | A kind of quaternary halogen amine antibacterial precursor, preparation and the application process immobilized for inactive surfaces | 大连理工大学 | 2016-12-14 | — | — | CN | claimed |
| CN-120060434-A | Sulfite conversion solution, kit and sulfite conversion method of DNA | 博尔诚（北京）科技有限公司 | 2025-05-30 | — | — | CN | disclosed |
| CN-117736083-A | Method for preparing 2, 4-dichloro-5-fluorobenzoic acid and 2, 6-dichloro-3-fluorobenzoic acid by taking 2, 4-dichloro-5-fluoroacetophenone crystallization mother liquor as raw material | 浙江工业大学 | 2024-03-22 | — | — | CN | disclosed |
| CN-113861007-B | Method for disposing 2-chloro-6 fluorobenzaldehyde distillation residues | 浙江大洋生物科技集团股份有限公司 | 2023-04-25 | — | — | CN | disclosed |
| CN-113861007-B | Method for disposing 2-chloro-6 fluorobenzaldehyde distillation residues | 浙江大洋生物科技集团股份有限公司 | 2023-04-25 | — | — | CN | disclosed |
| US-11590197-B2 | Agents targeting inhibitor of apoptosis proteins | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-02-28 | — | — | US | disclosed |
| CN-104208848-A | Golf ball | DUNLOP SPORTS CO LTD | 2014-12-17 | — | — | CN | disclosed |
| CN-103901149-A | Method for detecting 2,3,4,5-tetrafluoro-4-hydroxybenzoic acid tracer agent in oil field produced water | CHINA NAT OFFSHORE OIL CORP | 2014-07-02 | — | — | CN | disclosed |
| CN-103182162-A | Golf ball | DUNLOP SPORTS CO LTD | 2013-07-03 | — | — | CN | disclosed |
| CN-101838345-B | Fluorine-18 marked galactosylated chitosan compound and preparation method thereof | UNIV BEIJING NORMAL | 2012-05-30 | — | — | CN | disclosed |
| CN-101838345-A | Fluorine-18-labelled galactosylated chitosan compound and preparation method thereof | UNIV BEIJING NORMAL | 2010-09-22 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11590197-B2 | Agents targeting inhibitor of apoptosis proteins | XIAP, BIRC2, BIRC5 | TSHR 4550/4885DAO 3565/4885NAPRT 1796/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.