Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 20/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22397209 | 0.94 | RIPK1 (0.57) | RIPK1 | |
| SCHEMBL22397187 | 0.86 | RIPK1 (0.53) | RIPK1 | |
| SCHEMBL22370955 | 0.86 | RIPK1 (0.66) | RIPK1 | |
| SCHEMBL22371135 | 0.84 | PIK3CA (0.69) | RIPK1 | |
| SCHEMBL30468366 | 0.84 | PIK3CA (0.69) | RIPK1 | |
| SCHEMBL22371171 | 0.84 | RIPK1 (0.67) | RIPK1 | |
| Hydrochloric Acid SCHEMBL22371096 | 0.83 | PIK3CA (0.68) | RIPK1 | |
| SCHEMBL22370977 | 0.83 | RIPK1 (0.67) | RIPK1 | |
| SCHEMBL22397196 | 0.83 | RIPK1 (0.53) | RIPK1 | |
| SCHEMBL30468361 | 0.81 | RIPK1 (0.68) | RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3704118-A1 | AMINOIMIDAZOPYRIDAZINES AS KINASE INHIBITORS | Bristol-Myers Squibb Company (US) | 2020-09-09 | — | — | EP | disclosed |