SCHEMBL22398239

SCHEMBL22398239

CCOC(=O)CC(O)CCCCC(C)C

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 4/20 0.43
MGAM O43451 1/20 0.40
GAA P10253 1/20 0.40
SI P14410 1/20 0.40
MGAM2 Q2M2H8 1/20 0.40
ALDH1A1 P00352 3/20 0.38
TRPA1 O75762 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.37
CYP1A2 P05177 1/20 0.37
KDM4C Q9H3R0 2/20 0.37
KDM4A O75164 1/20 0.37
PHF8 Q9UPP1 1/20 0.37
KDM2A Q9Y2K7 1/20 0.37
KMT2A Q03164 2/20 0.36
CYP3A4 P08684 2/20 0.36
ALOX15 P16050 2/20 0.36
POLB P06746 1/20 0.36
TSHR P16473 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
FAAH O00519 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7603328 0.98 GPR84 (0.46) GPR84MGAMGAASIMGAM2
SCHEMBL22677576 0.98 GPR84 (0.46) GPR84MGAMGAASIMGAM2
SCHEMBL23673006 0.93 GPR84 (0.42) GPR84MGAMGAASIMGAM2
SCHEMBL6138869 0.89 GAA (0.43) MGAMGAASIMGAM2ALDH1A1
SCHEMBL21552037 0.87 GPR84 (0.46) GPR84MGAMGAASIMGAM2
SCHEMBL21551861 0.87 GPR84 (0.46) GPR84MGAMGAASIMGAM2
SCHEMBL21552018 0.87 GPR84 (0.46) GPR84MGAMGAASIMGAM2
SCHEMBL1242948 0.87 GPR84 (0.58) GPR84MGAMGAASIMGAM2
SCHEMBL22475413 0.87 GPR84 (0.44) GPR84MGAMGAASIMGAM2
SCHEMBL22398261 0.86 GPR84 (0.41) GPR84MGAMGAASIMGAM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11279733-B2 Peptide antibiotics THE UNIVERSITY OF QUEENSLAND (AU) 2022-03-22 US disclosed
US-11279733-B2 Peptide antibiotics THE UNIVERSITY OF QUEENSLAND (AU) 2022-03-22 US disclosed
US-20200361994-A1 PEPTIDE ANTIBIOTICS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2020-11-19 US disclosed
US-20200361994-A1 PEPTIDE ANTIBIOTICS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2020-11-19 US disclosed
EP-3704135-A1 PEPTIDE ANTIBIOTICS The University of Queensland (AU) 2020-09-09 EP disclosed
CN-111527100-A Peptide antibiotics 昆士兰大学 2020-08-11 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200361994-A1 PEPTIDE ANTIBIOTICS NGLY1, VIP, PEPD GPR84 2436/4885MGAM 137/4885GAA 1268/4885
US-11279733-B2 Peptide antibiotics NGLY1, VIP, PEPD GPR84 2436/4885MGAM 137/4885GAA 1268/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.