SCHEMBL22401705

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL29600727	0.85	ALDH1A1 (0.40)	ALDH1A1SMN1; SMN2KDM4EGLAHPGD
	SCHEMBL571871	0.85	ALDH1A1 (0.40)	ALDH1A1SMN1; SMN2KDM4EGLAHPGD
	SCHEMBL30690930	0.80	HDAC6 (0.37)	ALDH1A1SMN1; SMN2KDM4EGLAHPGD
	SCHEMBL21523292	0.79	HDAC6 (0.39)	ALDH1A1SMN1; SMN2KDM4EGLAHPGD
	SCHEMBL29751992	0.76	HDAC6 (0.44)	ALDH1A1KDM4EMAPTMAPK1HDAC6
	SCHEMBL10808625	0.75	ALDH1A1 (0.41)	ALDH1A1SMN1; SMN2KDM4EGLAHPGD
	SCHEMBL10808616	0.75	KDM4E (0.41)	ALDH1A1SMN1; SMN2KDM4EGLAHPGD
	SCHEMBL10479158	0.73	MAPT (0.52)	ALDH1A1SMN1; SMN2KDM4EGLAHPGD
	SCHEMBL2210085	0.72	MAPT (0.51)	ALDH1A1SMN1; SMN2KDM4EGLAHPGD
	SCHEMBL29600466	0.72	MAPT (0.51)	ALDH1A1SMN1; SMN2KDM4EGLAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.