Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.74 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.74 |
| ▸ | MAPT | P10636 | 2/20 | 0.74 |
| ▸ | LMNA | P02545 | 1/20 | 0.74 |
| ▸ | HDAC1 | Q13547 | 8/20 | 0.67 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.67 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.67 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.67 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.67 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.67 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.67 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.67 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.67 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.67 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.67 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | CASP3 | P42574 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.55 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8153235 | 1.00 | TDP1 (0.74) | TDP1L3MBTL1MAPTLMNAHDAC1 | |
| SCHEMBL12989353 | 1.00 | TDP1 (0.74) | TDP1L3MBTL1MAPTLMNAHDAC1 | |
| SCHEMBL10457866 | 1.00 | TDP1 (0.74) | TDP1L3MBTL1MAPTLMNAHDAC1 | |
| SCHEMBL2035615 | 0.92 | TDP1 (0.67) | TDP1L3MBTL1MAPTLMNAHDAC1 | |
| SCHEMBL27516050 | 0.86 | TDP1 (1.00) | TDP1L3MBTL1MAPTLMNAHDAC1 | |
| SCHEMBL9057671 | 0.86 | TDP1 (1.00) | TDP1L3MBTL1MAPTLMNAHDAC1 | |
| SCHEMBL8519287 | 0.86 | TDP1 (1.00) | TDP1L3MBTL1MAPTLMNAHDAC1 | |
| SCHEMBL276675 | 0.84 | TDP1 (0.59) | TDP1L3MBTL1MAPTLMNAHDAC1 | |
| SCHEMBL7068671 | 0.84 | TDP1 (0.95) | TDP1L3MBTL1MAPTLMNAHDAC1 | |
| SCHEMBL31612315 | 0.84 | TDP1 (0.71) | TDP1L3MBTL1MAPTLMNAHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011101274-A1 | STABILIZER SYSTEM FOR FOAMING POLYMERS CONTAINING HALOGEN | IKA INNOVATIVE KUNSTSTOFFAUFBEREITUNG GMBH & CO. KG (DE) | 2011-08-25 | — | — | WO | disclosed |
| US-5340862-A | A polyvinyl chloride blends containing a powder of alkali metal hydrogen phosphate or pyrophosphate salt; synergistic | ELF ATOCHEM NORTH AMERICA, INC. (US) | 1994-08-23 | — | — | US | disclosed |