Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | CES1 | P23141 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2035615 | 0.88 | TDP1 (0.67) | TDP1MAPTLMNAL3MBTL1NR4A2 | |
| SCHEMBL10457866 | 0.84 | TDP1 (0.74) | TDP1MAPTLMNAL3MBTL1NR4A2 | |
| SCHEMBL12989353 | 0.84 | TDP1 (0.74) | TDP1MAPTLMNAL3MBTL1NR4A2 | |
| SCHEMBL8153235 | 0.84 | TDP1 (0.74) | TDP1MAPTLMNAL3MBTL1NR4A2 | |
| SCHEMBL2240191 | 0.84 | TDP1 (0.74) | TDP1MAPTLMNAL3MBTL1NR4A2 | |
| SCHEMBL719034 | 0.81 | NR4A2 (0.85) | TDP1MAPTLMNAL3MBTL1NR4A2 | |
| SCHEMBL30121738 | 0.81 | NR4A2 (0.85) | TDP1MAPTLMNAL3MBTL1NR4A2 | |
| SCHEMBL10556922 | 0.81 | TDP1 (0.57) | TDP1MAPTLMNAL3MBTL1NR4A2 | |
| SCHEMBL8575630 | 0.81 | TDP1 (0.57) | TDP1MAPTLMNAL3MBTL1NR4A2 | |
| SCHEMBL1941975 | 0.81 | TDP1 (0.57) | TDP1MAPTLMNAL3MBTL1NR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 354 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090300800-A1 | D-Amino Acid a Selectable Marker for Barley (Hordeum Vulgare L.) Transformation | BASF PLANT SCIENCE GMBH (DE) | 2009-12-03 | — | — | US | claimed |
| US-20070248996-A1 | Modulators of beta-amyloid peptide aggregation comprising D-amino acids | PARAECIS PHARMACEUTICALS, INC. (US) | 2007-10-25 | — | — | US | claimed |
| US-20060014696-A1 | Modulators of beta-amyloid peptide aggregation comprising D-amino acids | PRAECIS PHARMACEUTICALS, INC. (US) | 2006-01-19 | — | — | US | claimed |
| EP-0929574-B1 | MODULATORS OF beta-AMYLOID PEPTIDE AGGREGATION COMPRISING D-AMINO ACIDS | PRAECIS PHARM INC (US) | 2005-06-29 | — | — | EP | claimed |
| EP-0898575-B1 | A COMBINATORIAL PROTECTING GROUP STRATEGY FOR MULTIFUNCTIONAL MOLECULES | KOESTER HUBERT DR (US) | 2004-12-29 | — | — | EP | claimed |
| US-6828435-B2 | Three blocking groups are independently removable under 3 different conditions; using new protection schemes and solid phase synthesis, oligonucleotides are obtained in 5' to 3' direction using phosphoamidites and avoiding depurination | HK PHARMACEUTICALS, INC. | 2004-12-07 | — | — | US | claimed |
| EP-1126833-A4 | OXADIAZOLE, THIADIAZOLE AND TRIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | TREGA BIOSCIENCES INC (US) | 2004-09-08 | — | — | EP | claimed |
| US-20040142946-A1 | Modified nucleosides and nucleotides and use thereof | CHATTOPADHYAYA JYOTI (SE) | 2004-07-22 | — | — | US | claimed |
| EP-0679196-B1 | DNA SEQUENCING BY MASS SPECTROMETRY | SEQUENOM INC (US) | 2004-05-26 | — | — | EP | claimed |
| US-20030194741-A1 | COMBINATORIAL PROTECTING GROUP STRATEGY FOR MULTIFUNCTIONAL MOLECULES | CAPROTEC BIOANALYTICS GMBH (DE) | 2003-10-16 | — | — | US | claimed |
| EP-0679196-A1 | DNA SEQUENCING BY MASS SPECTROMETRY | SEQUENOM, INC. (US) | 1995-11-02 | — | — | EP | claimed |
| EP-0648220-A1 | DEUTERATED NUCLEOSIDES | CHATTOPADHYAYA, Jyoti (SE) | 1995-04-19 | — | — | EP | claimed |
| EP-0456514-B1 | 2-Fluoroneplanocin A and its production | ASAHI CHEMICAL IND (JP) | 1994-10-19 | — | — | EP | claimed |
| WO-1994016101-A2 | DNA SEQUENCING BY MASS SPECTROMETRY | KOESTER HUBERT (US) | 1994-07-21 | — | — | WO | claimed |
| WO-1994010128-A1 | NOVEL PHOTOREACTIVE PROTECTING GROUPS | AFFYMAX TECHNOLOGIES N.V. (AN) | 1994-05-11 | — | — | WO | claimed |
| US-5279818-A | Permanent waving with silicones | DOW CORNING CORPORATION (US) | 1994-01-18 | — | — | US | claimed |
| WO-1993025566-A1 | DEUTERATED NUCLEOSIDES | CHATTOPADHYAYA JYOTI (SE) | 1993-12-23 | — | — | WO | claimed |
| WO-1992011276-A1 | NOVEL SYNTHESIS OF 2'-'UP' FLUORINATED 2''-DEOXY-ARABINOFURANOSYLPURINES | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1992-07-09 | — | — | WO | claimed |
| EP-0456514-A1 | 2-Fluoroneplanocin A and its production | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1991-11-13 | — | — | EP | claimed |
| US-4495346-A | CATALYTICALLY COUPLING TWO MONOSACCHARIDES | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1985-01-22 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070248996-A1 | Modulators of beta-amyloid peptide aggregation comprising D-amino acids | APP, IAPP, BACE1 | TDP1 1980/4885MAPT 121/4885LMNA 1617/4885 |
| US-20040142946-A1 | Modified nucleosides and nucleotides and use thereof | RNASEH1, RNASEL, NSUN2 | TDP1 99/4885MAPT 4857/4885LMNA 384/4885 |
| US-20030194741-A1 | COMBINATORIAL PROTECTING GROUP STRATEGY FOR MULTIFUNCTIONAL MOLECULES | ADAR, RNMT, ATIC | TDP1 3076/4885MAPT 2388/4885LMNA 2407/4885 |
| US-20060014696-A1 | Modulators of beta-amyloid peptide aggregation comprising D-amino acids | APP, IAPP, BACE1 | TDP1 1980/4885MAPT 121/4885LMNA 1617/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.