Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL160831 | 0.89 | NAMPT (1.00) | NAMPT | |
| Formamide SCHEMBL28161716 | 0.87 | NAMPT (0.76) | NAMPTCYP2C9 | |
| SCHEMBL22402284 | 0.87 | NAMPT (0.85) | NAMPT | |
| SCHEMBL164529 | 0.87 | NAMPT (1.00) | NAMPTCYP2C9 | |
| SCHEMBL161695 | 0.87 | NAMPT (1.00) | NAMPT | |
| SCHEMBL163353 | 0.87 | NAMPT (1.00) | NAMPT | |
| SCHEMBL163348 | 0.87 | NAMPT (1.00) | NAMPTCYP2C9 | |
| SCHEMBL166005 | 0.86 | NAMPT (1.00) | NAMPTCYP2C9 | |
| SCHEMBL162944 | 0.86 | NAMPT (1.00) | NAMPT | |
| SCHEMBL22402228 | 0.86 | NAMPT (0.84) | NAMPTCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200283403-A1 | NOVEL COMPOUNDS AND COMPOSITIONS FOR THE INHIBITION OF NAMPT | Valo Health, LLC | 2020-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200283403-A1 | NOVEL COMPOUNDS AND COMPOSITIONS FOR THE INHIBITION OF NAMPT | NAMPT, HAMP, NQO1 | NAMPT 1/4885CYP2C9 1055/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.