SCHEMBL2240266

SCHEMBL2240266

ClCCc1cccnc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL178021 0.98 CHRNA7 (0.61)
SCHEMBL742284 0.87 CYP2A6 (0.66)
SCHEMBL29485692 0.85 CHRNA7 (0.74)
SCHEMBL724866 0.85 CHRNA7 (0.74)
Hydrochloric Acid SCHEMBL1872033 0.85 CYP2A6 (0.63)
SCHEMBL826569 0.85 TDP1 (0.67)
SCHEMBL8309884 0.84 CHRNA7 (0.47)
SCHEMBL742233 0.84 HRH1 (0.68)
SCHEMBL10350863 0.84 HRH1 (0.68)
SCHEMBL10349750 0.84 HRH1 (0.68)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12570860-B2 Two-component treatment agent, treatment method for making metal surface antibacterial and antibacterial treatment agent TOKYO OHKA KOGYO CO., LTD. (JP) 2026-03-10 US disclosed
US-20240336590-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH APJ RECEPTOR ACTIVITY ANNAPURNA BIO, INC. 2024-10-10 US disclosed
EP-4257593-A1 CHIRAL MULTIDENTATE LIGAND AND USE THEREOF IN ASYMMETRIC HYDROGENATION SHENZHEN CATALYS TECHNOLOGY CO., LTD. (CN) 2023-10-11 EP disclosed
US-11724997-B2 Compounds and compositions for treating conditions associated with APJ receptor activity ANNAPURNA BIO, INC. (US) 2023-08-15 US disclosed
US-11724997-B2 Compounds and compositions for treating conditions associated with APJ receptor activity ANNAPURNA BIO, INC. (US) 2023-08-15 US disclosed
US-11724997-B2 Compounds and compositions for treating conditions associated with APJ receptor activity ANNAPURNA BIO, INC. (US) 2023-08-15 US disclosed
US-20220267615-A1 TWO-COMPONENT TREATMENT AGENT, TREATMENT METHOD FOR MAKING METAL SURFACE ANTIBACTERIAL AND ANTIBACTERIAL TREATMENT AGENT TOKYO OHKA KOGYO CO., LTD. (JP) 2022-08-25 US disclosed
US-20210053936-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH APJ RECEPTOR ACTIVITY ANNAPURNA BIO, INC. 2021-02-25 US disclosed
US-20210053936-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH APJ RECEPTOR ACTIVITY ANNAPURNA BIO, INC. 2021-02-25 US disclosed
EP-3759095-A1 COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH APJ RECEPTOR ACTIVITY Annapurna Bio Inc. (US) 2021-01-06 EP disclosed
US-20070299258-A1 THERAPEUTIC COMPOUNDS AND THEIR USE IN CANCER MYRIAD GENETICS, INCORPORATED (US) 2007-12-27 US disclosed
WO-2007134298-A2 THERAPEUTIC COMPOUNDS AND THEIR USE IN CANCER MYRIAD GENETICS, INC. (US) 2007-11-22 WO disclosed
CN-1083432-C Alpha-unsaturated amines, their production and use TAKEDA CHEMICAL INDUSTRIES LTD (JP) 2002-04-24 CN disclosed
US-6133443-A HAVING VASODILATING ACTIVITY AND HYPOTENSIVE ACTIVITY; EXCELLENT IN WATER SOLUBILITY; USEFUL AS DRUGS FOR CIRCULATORY SYSTEM DISORDERS SUCH AS A HYPOTENSOR OR VASODILATOR MERCIAN CORPORATION (JP) 2000-10-17 US disclosed
CN-1036649-C Alpha-unsaturated amines, their production and use TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1997-12-10 CN disclosed
US-5264437-A Antiinflammatory agents, immunosuppressants or antiallergens SYNTEX (U.S.A.) INC. (US) 1993-11-23 US disclosed
US-4511720-A HYPOTENSIVE AGENTS HOFFMANN-LA ROCHE INC. (US) 1985-04-16 US disclosed
US-4355033-A TREATMENT OF HYPERTENSION HOFFMAN-LA ROCHE INC. (US) 1982-10-19 US disclosed
US-4244957-A HYPOTENSIVE AGENTS HOFFMAN-LA ROCHE INC. (US) 1981-01-13 US disclosed
US-4198504-A ANTIBIOTIC BRISTOL-MYERS COMPANY (US) 1980-04-15 US disclosed