Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | KDM5A | P29375 | 1/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22402968 | 0.73 | PARP1 (0.37) | KDM4EALDH1A1NSD2MAPK1CYP2C9 | |
| SCHEMBL21836692 | 0.70 | POLB (0.37) | KDM4EALDH1A1NSD2MAPK1CYP2C9 | |
| SCHEMBL11643960 | 0.67 | PTGS2 (0.43) | POLBGAA | |
| SCHEMBL11643633 | 0.64 | PTGS2 (0.46) | ALDH1A1MAPK1 | |
| SCHEMBL11743978 | 0.57 | POLB (0.32) | KDM4EALDH1A1MAPK1CYP1A2POLB | |
| SCHEMBL14738537 | 0.57 | POLB (0.52) | KDM4EALDH1A1MAPK1CYP1A2POLB | |
| SCHEMBL13160725 | 0.54 | POLB (0.53) | KDM4EALDH1A1CYP1A2POLBGAA | |
| SCHEMBL14557158 | 0.54 | POLB (0.43) | KDM4EMAPK1CYP1A2POLBGAA | |
| SCHEMBL9748738 | 0.54 | MAPK1 (0.45) | KDM4EALDH1A1NSD2MAPK1POLB | |
| SCHEMBL23937891 | 0.54 | KDM4E (0.33) | KDM4EALDH1A1KDM5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11786575-B2 | Endoparasitic depsipeptides | ZOETIS SERVICES LLC (US) | 2023-10-17 | — | — | US | disclosed |
| US-20220211802-A1 | Endoparasitic Depsipeptides | ZOETIS SERVICES LLC | 2022-07-07 | — | — | US | disclosed |
| US-11331369-B2 | Endoparasitic depsipeptides | ZOETIS SERVICES LLC (US) | 2022-05-17 | — | — | US | disclosed |
| US-20200282016-A1 | Endoparasitic Depsipeptides | ZOETIS SERVICES LLC | 2020-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11786575-B2 | Endoparasitic depsipeptides | VIP, PREP, NGLY1 | KDM4E 3941/4885ALDH1A1 3102/4885NSD2 4605/4885 |
| US-20200282016-A1 | Endoparasitic Depsipeptides | VIP, PREP, NGLY1 | KDM4E 3941/4885ALDH1A1 3102/4885NSD2 4605/4885 |
| US-20220211802-A1 | Endoparasitic Depsipeptides | VIP, PREP, NGLY1 | KDM4E 3941/4885ALDH1A1 3102/4885NSD2 4605/4885 |
| US-11331369-B2 | Endoparasitic depsipeptides | VIP, PREP, NGLY1 | KDM4E 3941/4885ALDH1A1 3102/4885NSD2 4605/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.