Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.35 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.35 |
| ▸ | PADI1 | Q9ULC6 | 1/20 | 0.33 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19274145 | 1.00 | SIGMAR1 (0.40) | SIGMAR1CHRM3CHRM5SMN1; SMN2PLA2G10 | |
| SCHEMBL19422330 | 1.00 | SIGMAR1 (0.40) | SIGMAR1CHRM3CHRM5SMN1; SMN2PLA2G10 | |
| SCHEMBL21917398 | 0.95 | SIGMAR1 (0.36) | SIGMAR1CHRM3CHRM5SMN1; SMN2PLA2G10 | |
| SCHEMBL751886 | 0.88 | CHRM3 (0.41) | SIGMAR1CHRM3CHRM5SMN1; SMN2PLA2G10 | |
| SCHEMBL1149470 | 0.87 | SIGMAR1 (0.49) | SIGMAR1CHRM3CHRM5SMN1; SMN2PLA2G10 | |
| SCHEMBL583320 | 0.87 | SIGMAR1 (0.49) | SIGMAR1CHRM3CHRM5SMN1; SMN2PLA2G10 | |
| SCHEMBL18752979 | 0.86 | PLA2G10 (0.34) | CHRM3PLA2G10PLA2G5KDM4EALDH1A1 | |
| SCHEMBL4771744 | 0.85 | SIGMAR1 (0.47) | SIGMAR1CHRM3CHRM5SMN1; SMN2PLA2G10 | |
| Hydrochloric Acid SCHEMBL8209880 | 0.85 | SIGMAR1 (0.47) | SIGMAR1CHRM3CHRM5SMN1; SMN2PLA2G10 | |
| Bromide SCHEMBL583318 | 0.85 | SIGMAR1 (0.47) | SIGMAR1CHRM3CHRM5SMN1; SMN2PLA2G10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10975060-B2 | High relaxivity gadolinium chelate compounds for use in magnetic resonance imaging | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2021-04-13 | — | — | US | disclosed |
| US-20200283420-A1 | HIGH RELAXIVITY GADOLINIUM CHELATE COMPOUNDS FOR USE IN MAGNETIC RESONANCE IMAGING | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2020-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200283420-A1 | HIGH RELAXIVITY GADOLINIUM CHELATE COMPOUNDS FOR USE IN MAGNETIC RESONANCE IMAGING | RXFP1, RXFP2, RXFP3 | SIGMAR1 2756/4885CHRM3 163/4885CHRM5 309/4885 |
| US-10975060-B2 | High relaxivity gadolinium chelate compounds for use in magnetic resonance imaging | RXFP1, RXFP2, RXFP3 | SIGMAR1 2756/4885CHRM3 163/4885CHRM5 309/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.