SCHEMBL22403594

SCHEMBL22403594

c1ccc(-c2ccccc2N(c2cccc(N(c3cccc(C4(c5ccccc5)c5ccccc5-c5ccccc54)c3)c3ccc4c(c3)C(c3ccccc3)(c3ccccc3)c3ccccc3-4)c2)c2cccc3c2-c2ccccc2C3(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.31

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.31
MEN1 O00255 1/20 0.31
LMNA P02545 1/20 0.31
MAPT P10636 1/20 0.31
OPRK1 P41145 1/20 0.31
KMT2A Q03164 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
PDK2 Q15119 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25563237 0.94 KDM4E (0.31) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL22403477 0.94 KDM4E (0.33) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL17854072 0.94 KDM4E (0.34) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL17854135 0.93 KDM4E (0.33) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL16544705 0.93 KDM4E (0.33) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL22403341 0.93 KDM4E (0.30) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL22403475 0.92 KDM4E (0.31) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL17854077 0.92 PDK2 (0.33) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL17854146 0.91 PDK2 (0.32) KDM4EMEN1LMNAMAPTOPRK1
SCHEMBL17854130 0.91 KDM4E (0.35) KDM4EMEN1LMNAMAPTOPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200287140-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING THE SAME, AND AN ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2020-09-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200287140-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING THE SAME, AND AN ELECTRONIC DEVICE THEREOF OR51E2, PIEZO1, OR10J3 KDM4E 730/4885MEN1 520/4885LMNA 1511/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.