⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20469209 | 0.64 | — | — | |
| SCHEMBL12402311 | 0.62 | — | — | |
| SCHEMBL14135302 | 0.60 | — | — | |
| SCHEMBL13152014 | 0.58 | — | — | |
| SCHEMBL2632482 | 0.57 | — | — | |
| SCHEMBL21583896 | 0.55 | — | — | |
| SCHEMBL22796230 | 0.53 | — | — | |
| SCHEMBL19266821 | 0.53 | — | — | |
| SCHEMBL16692795 | 0.51 | — | — | |
| SCHEMBL13536968 | 0.46 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11319305-B2 | Pyrimidine sulfamide derivative and preparation method and medical application thereof | Shijiazhuang Sagacity New Drug Development Co., Ltd. (CN) | 2022-05-03 | — | — | US | disclosed |
| US-20200283425-A1 | PYRIMIDINE SULFAMIDE DERIVATIVE AND PREPARATION METHOD AND MEDICAL APPLICATION THEREOF | Wuxi Biocity Biopharmaceutics Co., Ltd. (CN) | 2020-09-10 | — | — | US | disclosed |