SCHEMBL224044

SCHEMBL224044

CCCCCCCCCCOC(=O)CC#N

nearest known ligand 0.62

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 1/20 0.62
RAD52 P43351 1/20 0.53
NPSR1 Q6W5P4 1/20 0.53
DGKA P23743 1/20 0.52
FAAH O00519 2/20 0.51
HTR2C P28335 1/20 0.50
PRSS1 P07477 1/20 0.49
PRSS2 P07478 1/20 0.49
PRSS3 P35030 1/20 0.49
EPHX1 P07099 1/20 0.48
TSHR P16473 3/20 0.47
CES2 O00748 1/20 0.46
HCAR2 Q8TDS4 1/20 0.44
DNM1 Q05193 1/20 0.43
ALDH1A1 P00352 1/20 0.43
LMNA P02545 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1961633 1.00 NAAA (0.62) NAAARAD52NPSR1DGKAFAAH
SCHEMBL1961134 1.00 NAAA (0.62) NAAARAD52NPSR1DGKAFAAH
SCHEMBL1961372 1.00 NAAA (0.62) NAAARAD52NPSR1DGKAFAAH
SCHEMBL1960270 1.00 NAAA (0.62) NAAARAD52NPSR1DGKAFAAH
SCHEMBL1961180 1.00 NAAA (0.62) NAAARAD52NPSR1DGKAFAAH
SCHEMBL1958216 1.00 NAAA (0.62) NAAARAD52NPSR1DGKAFAAH
SCHEMBL634649 1.00 NAAA (0.62) NAAARAD52NPSR1DGKAFAAH
SCHEMBL9019593 1.00 NAAA (0.62) NAAARAD52NPSR1DGKAFAAH
SCHEMBL10901661 1.00 NAAA (0.62) NAAARAD52NPSR1DGKAFAAH
SCHEMBL10901502 1.00 NAAA (0.62) NAAARAD52NPSR1DGKAFAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115151527-B Process for the preparation of cyanoacetic esters 汉高股份有限及两合公司 2025-05-13 CN disclosed
CN-115151527-A Process for the preparation of cyanoacetic esters 汉高股份有限及两合公司 2022-10-04 CN disclosed
US-9976103-B2 Lubricating composition containing an antiwear agent THE LUBRIZOL CORPORATION (US) 2018-05-22 US disclosed
EP-2513269-B1 LUBRICATING COMPOSITION CONTAINING AN ANTIWEAR AGENT LUBRIZOL CORP (US) 2017-10-25 EP disclosed
US-9708563-B2 Lubricating composition containing an antiwear agent THE LUBRIZOL CORPORATION (US) 2017-07-18 US disclosed
US-20150267140-A1 LUBRICATING COMPOSITION CONTAINING AN ANTIWEAR AGENT LUBRIZOL CORP (US) 2015-09-24 US disclosed
US-20130172221-A1 Lubricating Composition Containing an Antiwear Agent THE LUBRIZOL CORPORATION (US) 2013-07-04 US disclosed
EP-1993626-B1 IMPLANTABLE MEDICAL DEVICE COATED WITH BIOACTIVE AGENT COOK MEDICAL TECHNOLOGIES LLC (US) 2013-01-23 EP disclosed
US-20120309657-A1 Lubricating Composition Containing an Antiwear Agent THE LUBRIZOL CORPORATION (US) 2012-12-06 US disclosed
EP-2513269-A1 LUBRICATING COMPOSITION CONTAINING AN ANTIWEAR AGENT The Lubrizol Corporation (US) 2012-10-24 EP disclosed
WO-2004003044-A2 DYNAMERS: POLYMERIC MATERIALS EXHIBITING REVERSIBLE FORMATION AND COMPONENT EXCHANGE LEHN JEAN-MARIE (FR) 2004-01-08 WO disclosed
US-6271410-B1 REACTING THE CORRESPONDING ALCOHOL WITH CYANOACETIC ACID IN THE PRESENCE OF AN ACID CATALYST CREANOVA INC. 2001-08-07 US disclosed
US-6136876-A SHRINKAGE INHIBITION AIR PRODUCTS AND CHEMICALS (US) 2000-10-24 US disclosed
EP-1002816-A2 Weak bronsted acid derivatives for improving dimensional stability of polyurethane flexible foams AIR PRODUCTS AND CHEMICALS, INC. (US) 2000-05-24 EP disclosed
US-4622332-A Asymmetric diesters of Hantzsch dihydropyridines with hypotensive activity BAYER AKTIENGESELLSCHAFT (DE) 1986-11-11 US disclosed
US-4421929-A POLYIMIDES THE DOW CHEMICAL COMPANY (US) 1983-12-20 US disclosed
US-4309500-A CONTAINING ABSORBER OF ULTRAVIOLET LIGHT FUJI PHOTO FILM CO., LTD. (JP) 1982-01-05 US disclosed
US-4271288-A TETRACARBOXYLIC ACID BONDED TO ARYLENE MOIETY VIA METHYLENE GROUPS THE DOW CHEMICAL COMPANY (US) 1981-06-02 US disclosed
US-4263209-A FROM ALDEHYDES; INTERMEDIATES FOR POLYMERS THE DOW CHEMICAL COMPANY (US) 1981-04-21 US disclosed
US-4239694-A Bis-dicyanoalkyl arene compounds THE DOW CHEMICAL COMPANY (US) 1980-12-16 US disclosed