Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.84 |
| ▸ | USP2 | O75604 | 2/20 | 0.84 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.84 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.84 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.84 |
| ▸ | PTGES | O14684 | 4/20 | 0.71 |
| ▸ | CRYAB | P02511 | 3/20 | 0.70 |
| ▸ | LMNA | P02545 | 1/20 | 0.70 |
| ▸ | FNTA | P49354 | 1/20 | 0.65 |
| ▸ | FNTB | P49356 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.57 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.57 |
| ▸ | PREP | P48147 | 1/20 | 0.55 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.55 |
| ▸ | CRYAA | P02489 | 1/20 | 0.55 |
| ▸ | BACE1 | P56817 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL415761 | 0.91 | MAPT (1.00) | MAPTUSP2ALDH1A1CYP3A4ALOX15 | |
| SCHEMBL6130526 | 0.91 | MAPT (1.00) | MAPTUSP2ALDH1A1CYP3A4ALOX15 | |
| SCHEMBL17431708 | 0.91 | MAPT (1.00) | MAPTUSP2ALDH1A1CYP3A4ALOX15 | |
| SCHEMBL2340127 | 0.91 | MAPT (1.00) | MAPTUSP2ALDH1A1CYP3A4ALOX15 | |
| SCHEMBL415760 | 0.91 | MAPT (1.00) | MAPTUSP2ALDH1A1CYP3A4ALOX15 | |
| SCHEMBL19194140 | 0.91 | MAPT (1.00) | MAPTUSP2ALDH1A1CYP3A4ALOX15 | |
| SCHEMBL5666302 | 0.91 | MAPT (1.00) | MAPTUSP2ALDH1A1CYP3A4ALOX15 | |
| SCHEMBL4735041 | 0.89 | MAPT (0.85) | MAPTUSP2ALDH1A1CYP3A4ALOX15 | |
| SCHEMBL4735043 | 0.89 | MAPT (0.85) | MAPTUSP2ALDH1A1CYP3A4ALOX15 | |
| SCHEMBL21285187 | 0.88 | MAPT (0.84) | MAPTUSP2ALDH1A1CYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200281944-A1 | Combinations Of Lanosterol Or 25-Hydroxycholesterol Including Derivatives Thereof Useful In The Treatment Of Lens Disorders | PIRAEE MAHMOOD (CA) | 2020-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200281944-A1 | Combinations Of Lanosterol Or 25-Hydroxycholesterol Including Derivatives Thereof Useful In The Treatment Of Lens Disorders | CYP46A1, LSS, CYP27A1 | MAPT 555/4885USP2 2602/4885ALDH1A1 3533/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.