SCHEMBL2240675

SCHEMBL2240675

C=CCCCC[SiH](OCC)OCC

nearest known ligand 0.44

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.44
ALDH1A1 P00352 3/20 0.42
LMNA P02545 1/20 0.34
LPAR3 Q9UBY5 2/20 0.31
LPAR2 Q9HBW0 1/20 0.31
ABCC4 O15439 1/20 0.30
MAPT P10636 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8515574 0.98 TSHR (0.48) TSHRALDH1A1LMNALPAR3LPAR2
SCHEMBL6037318 0.98 TSHR (0.48) TSHRALDH1A1LMNALPAR3LPAR2
SCHEMBL387079 0.98 TSHR (0.48) TSHRALDH1A1LMNALPAR3LPAR2
SCHEMBL6037421 0.98 TSHR (0.48) TSHRALDH1A1LMNALPAR3LPAR2
SCHEMBL8512174 0.98 TSHR (0.48) TSHRALDH1A1LMNALPAR3LPAR2
SCHEMBL8510977 0.98 TSHR (0.48) TSHRALDH1A1LMNALPAR3LPAR2
SCHEMBL4380232 0.98 TSHR (0.48) TSHRALDH1A1LMNALPAR3LPAR2
SCHEMBL8511146 0.98 TSHR (0.48) TSHRALDH1A1LMNALPAR3LPAR2
SCHEMBL6037315 0.98 TSHR (0.48) TSHRALDH1A1LMNALPAR3LPAR2
SCHEMBL3336746 0.98 TSHR (0.48) TSHRALDH1A1LMNALPAR3LPAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119842205-A Flame-retardant PC/ABS composite material for automobile and preparation process thereof 常州涵洋高分子材料科技有限公司 2025-04-18 CN claimed
EP-0974596-B1 Method for preparation of alkoxysilanes having reduced halide content DOW CORNING (US) 2003-03-05 EP claimed
EP-0974596-A2 Method for preparation of alkoxysilanes having reduced halide content DOW CORNING CORPORATION (US) 2000-01-26 EP claimed
CN-119842205-A Flame-retardant PC/ABS composite material for automobile and preparation process thereof 常州涵洋高分子材料科技有限公司 2025-04-18 CN disclosed
WO-2025023143-A1 GLASS CLOTH TREATMENT LIQUID AND SURFACE TREATED GLASS CLOTH 信越化学工業株式会社 2025-01-30 WO disclosed
EP-2032588-B1 METHOD FOR PREPARATION OF ALKOXYSILANES HAVING REDUCED HALIDE CONTENT DOW CORNING (US) 2012-08-08 EP disclosed
US-20120136082-A1 BINDING AGENTS BASED ON HIGHLY BRANCHED POLYOLEFINS COMPRISING SILANE GROUPS WACKER CHEMIE AG (DE) 2012-05-31 US disclosed
US-7994250-B2 Vinyl-urethane copolymers with intermediary linkage segments having silicon-oxygen bonds and production methods thereof KONISHI CO., LTD. (JP) 2011-08-09 US disclosed
US-20090326151-A1 HAIR COSMETIC KONISHI CO., LTD. (JP) 2009-12-31 US disclosed
US-20090270646-A1 METHOD FOR PREPARATION OF ALKOXYSILANES HAVING REDUCED HALIDE DOW CORNING CORPORATION 2009-10-29 US disclosed
EP-2039347-A1 COSMETIC HAIR PREPARATION Shiseido Company, Limited (JP) 2009-03-25 EP disclosed
EP-0863146-B1 Method of making organosilicon carbonyl compounds DOW CORNING (US) 2003-02-19 EP disclosed
EP-0974596-A2 Method for preparation of alkoxysilanes having reduced halide content DOW CORNING CORPORATION (US) 2000-01-26 EP disclosed
US-5914421-A Method for preparation of alkoxysilanes having reduced halide content DOW CORNING CORPORATION (US) 1999-06-22 US disclosed
US-5880304-A Method of making organosilicon carbonyl compounds DOW CORNING CORPORATION (US) 1999-03-09 US disclosed
EP-0870774-A2 Method of making silicone-organic block copolymers DOW CORNING CORPORATION (US) 1998-10-14 EP disclosed
EP-0863146-A2 Method of making organosilicon carbonyl compounds DOW CORNING CORPORATION (US) 1998-09-09 EP disclosed
US-5789516-A ADDITION-CONDENSATION POLYMERS DOW CORNING CORPORATION (US) 1998-08-04 US disclosed
US-5789503-A Polymerization of vinyl monomers from silanes and siloxanes DOW CORNING CORPORATION (US) 1998-08-04 US disclosed
US-5708115-A OZONIDE GROUPS, FREE RADICAL CATALYSTS DOW CORNING CORPORATION (US) 1998-01-13 US disclosed