SCHEMBL2240765

SCHEMBL2240765

BrCCCCCCCCCCCCN1c2ccccc2Oc2ccccc21

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIM1 P11309 4/20 0.50
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
SIGMAR1 Q99720 1/20 0.49
HDAC3 O15379 2/20 0.46
HDAC6 Q9UBN7 2/20 0.46
TUBB4A P04350 1/20 0.46
TUBB P07437 1/20 0.46
TUBA3C P0DPH7 1/20 0.46
HDAC4 P56524 1/20 0.46
TUBA1B P68363 1/20 0.46
TUBA4A P68366 1/20 0.46
TUBB4B P68371 1/20 0.46
TUBB3 Q13509 1/20 0.46
HDAC1 Q13547 1/20 0.46
TUBB2A Q13885 1/20 0.46
TUBB8 Q3ZCM7 1/20 0.46
TUBA3E Q6PEY2 1/20 0.46
TUBA1A Q71U36 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23174008 1.00 PIM1 (0.50) PIM1MEN1KMT2ATDP1SIGMAR1
SCHEMBL13308133 0.98 PIM1 (0.51) PIM1MEN1KMT2ATDP1SIGMAR1
SCHEMBL23144877 0.93 SIGMAR1 (0.51) PIM1MEN1KMT2ATDP1SIGMAR1
SCHEMBL28664202 0.88 PIM1 (0.45) PIM1MEN1KMT2ATDP1SIGMAR1
SCHEMBL1367274 0.85 HDAC8 (0.66) TDP1HDAC3HDAC6TUBB4ATUBB
SCHEMBL5464107 0.85 HDAC8 (0.66) TDP1HDAC3HDAC6TUBB4ATUBB
SCHEMBL32685462 0.85 SIGMAR1 (0.46) PIM1MEN1KMT2ATDP1SIGMAR1
SCHEMBL5711001 0.85 PIM1 (0.44) PIM1MEN1KMT2ASIGMAR1SMPD1
SCHEMBL5710987 0.85 PIM1 (0.44) PIM1MEN1KMT2ASIGMAR1SMPD1
SCHEMBL2254853 0.82 MEN1 (0.53) PIM1MEN1KMT2ATDP1SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2360758-B1 LITHIUM RECHARGEABLE ELECTROCHEMICAL CELL DOW GLOBAL TECHNOLOGIES LLC (US) 2014-02-26 EP disclosed
EP-2360758-B1 LITHIUM RECHARGEABLE ELECTROCHEMICAL CELL DOW GLOBAL TECHNOLOGIES LLC (US) 2014-02-26 EP disclosed
CN-101416344-B Lithium rechargeable electrochemical cell DOW GLOBAL TECHNOLOGIES INC 2011-11-23 CN disclosed
EP-2360758-A2 Lithium rechargeable electrochemical cell Dow Global Technologies LLC (US) 2011-08-24 EP disclosed
EP-2360758-A2 Lithium rechargeable electrochemical cell Dow Global Technologies LLC (US) 2011-08-24 EP disclosed
US-20090176162-A1 LITHIUM RECHARGEABLE ELECTROCHEMICAL CELL DOW GLOBAL TECHNOLOGIES LLC 2009-07-09 US disclosed
US-20090176162-A1 LITHIUM RECHARGEABLE ELECTROCHEMICAL CELL DOW GLOBAL TECHNOLOGIES LLC 2009-07-09 US disclosed
US-20090176162-A1 LITHIUM RECHARGEABLE ELECTROCHEMICAL CELL DOW GLOBAL TECHNOLOGIES LLC 2009-07-09 US disclosed
CN-101416344-A Lithium rechargeable electrochemical cell HIGH POWER LITHIUM S A (CH) 2009-04-22 CN disclosed
EP-2008336-A2 LITHIUM RECHARGEABLE ELECTROCHEMICAL CELL High Power Lithium S.A. (CH) 2008-12-31 EP disclosed
WO-2007116363-A2 LITHIUM RECHARGEABLE ELECTROCHEMICAL CELL HIGH POWER LITHIUM S.A. (CH) 2007-10-18 WO disclosed
WO-2007116363-A2 LITHIUM RECHARGEABLE ELECTROCHEMICAL CELL HIGH POWER LITHIUM S.A. (CH) 2007-10-18 WO disclosed